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Zero-mode waveguide

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In biophysics, a zero-mode waveguide is an optical waveguide that guides light energy into a volume that is small in all dimensions compared to the wavelength of the light. It is also known as a waveguide below-cutoff attenuator.[1] Zero-mode waveguides have been developed for rapid parallel sensing of zeptolitre sample volumes, as applied to gene sequencing, by Nanofluidics, Inc. (now Pacific Biosciences).[2]

References

  1. ^ D. H. Russell, IEEE Trans. Microwave Theory and Tech., Vol. 45, 2408 (1997).
  2. ^ Jan Kieleczawa (2004). DNA sequencing: optimizing the process and analysis. Jones & Bartlett Publishers. p. 190. ISBN 9780763747824.