Jump to content

User:Celefin/Work in progress

From Wikipedia, the free encyclopedia
< User:Celefin
This is an old revision of this page, as edited by Celefin (talk | contribs) at 13:14, 13 April 2009 (start ob/ob rewrite). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

The ob/ob or obese mouse is a mutant mouse that eats excessively, become profoundly obese, and develops type II diabetes. Identification of the gene mutated in ob led to the discovery of the hormone leptin, which is important in control of appetite.

The first ob mutant mouse arose spontaneously (by chance) in a colony at the Jackson Laboratory in 1949.[1]


  1. ^ Ingalls AM, Dickie MM, Snell GD (1950). "Obese, a new mutation in the house mouse". J. Hered. 41 (12): 317–8. PMID 14824537. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
Stub icon

This genetics article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=User:Celefin/Work_in_progress&oldid=283554008"