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Restriction fragment mass polymorphism

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Restriction Fragment Mass Polymorphism (RFMP) is a technology which digests DNA into oligonucleotide fregments, and detects variation of DNA sequences by molecular weight of the fragments. RFMP is a proprietary technolgy of GeneMatrix and can be utilized for genotyping of viruses, microorganisms, and human genome research.


References

  • Kim, Y (2005). "Population Genotyping of Hepatitis C Virus by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Analysis of Short DNA Fragments", Clinical Chemistry, 51: 1123-1131
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