Fourier shell correlation

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The three-dimensional Fourier Shell Correlation (FSC) measures the normalised cross correlation coefficient between two 3D volumes over corresponding shells in Fourier space, i.e., as a function of spatial frequency^[1]. The (modified) 3-sigma criterion indicates where the FSC systematically emerges above the expected random correlations of the background noise^[2].

^ Harauz, George; van Heel, Marin (1986). "Exact filters for general geometry three dimensional reconstruction". Optik. 78: 146–156.
^ van Heel, Marin; Michael, Michael. "Fourier shell correlation threshold criteria". Journal of Structural Biology. 151: 250–262.

[1] Harauz, George; van Heel, Marin (1986). "Exact filters for general geometry three dimensional reconstruction". Optik. 78: 146–156.

[2] van Heel, Marin; Michael, Michael. "Fourier shell correlation threshold criteria". Journal of Structural Biology. 151: 250–262.

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