Neuron-Restrictive Silencer Factor

NRSF bound to DNA and cofactors on each of its two cofactor binding domains

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Chromatin remodeling occurs, causing the gene to be 'turned off'

Template:PBB Neuron-Restrictive Silencer Factor, also known as NRSF, is a human gene.. It is also commonly referred to as the RE1-silencing transcription factor (REST).

Further reading

• Ooi L and Wood IC (2007). "Chromatin crosstalk in development and disease: lessons from REST". Nat. Rev. Genet. 8 (6(7)): 544–54. doi:10.1038/nrg2100. PMID 17572692.

External links

• REST+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.