3-hydroxybenzoate 2-monooxygenase

In enzymology, a 3-hydroxybenzoate 2-monooxygenase (EC 1.14.99.23) is an enzyme that catalyzes the chemical reaction

3-hydroxybenzoate + AH₂ + O₂ $\rightleftharpoons$ 2,3-dihydroxybenzoate + A + H₂O

The 3 substrates of this enzyme are 3-hydroxybenzoate, AH2, and O₂, whereas its 3 products are 2,3-dihydroxybenzoate, A, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is 3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating). Other names in common use include 3-hydroxybenzoate 2-hydroxylase, and 3-HBA-2-hydroxylase. This enzyme participates in benzoate degradation via hydroxylation.

References

• Daumy GO, McColl AS (1982). "Induction of 3-hydroxybenzoate 2-hydroxylase in a Pseudomonas testosteroni mutant". J. Bacteriol. 149: 384–5. PMID 7054148.

External links

The CAS registry number for this enzyme class is Template:CAS registry.