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Cleaved amplified polymorphic sequence

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The Cleaved Amplified Polymorphic Sequence or CAPS method is a technique in molecular biology for the analysis of genetic marker.

CAPS work on the principle that genetic differences between individuals can create or abolish restriction endonuclease restriction sites, and that these differences can be detected in the resulting DNA fragment length after digestion. For more information see RFLP.

http://www.ncbi.nlm.nih.gov/projects/genome/probe/doc/TechCAPS.shtml

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