Jump to content

Talk:X-linked recessive inheritance

Page contents not supported in other languages.
From Wikipedia, the free encyclopedia

Template:WikiProject GeneticsTemplate:MedGen

WikiProject iconMedicine Start‑class Mid‑importance
WikiProject iconThis article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.
StartThis article has been rated as Start-class on Wikipedia's content assessment scale.
MidThis article has been rated as Mid-importance on the project's importance scale.

Merge X-linked dominant, X-linked recessive, and Sex linkage into an article on "X-linked inheritance" or "X-linked disorders"?

What do people think about merging these topics? The X-linked dominant article is woefully lacking and the X-linked recessive article makes note of the fact that differences in X-inactivation can lead to phenotypic expression of an X-linked "recessive" trait in a "carrier" female. In many of these disorders female carriers DO have phenotypes (for example, carriers of a Duchenne Muscular Dystrophy gene mutation are at high risk for cardiomyopathy as adults) so the "recessive" label should not really be applied. The Sex linkage article seems to be an attempt to do this but would need to be overhauled.

Thoughts? Medical geneticist (talk) 22:18, 8 August 2008 (UTC)[reply]