Complement component 5
| Name = Complement component 5 | HGNCid = 1331 | Symbol = C5 | AltSymbols =; CPAMD4; MGC142298 | OMIM = 120900 | ECnumber = | Homologene = 20412 | MGIid = 96031 | GeneAtlas_image1 = PBB_GE_C5_205500_at_tn.png | Function = • endopeptidase inhibitor activity
• receptor binding
• chemokine activity
| Component = • extracellular region
• membrane attack complex
• extracellular space
| Process = • activation of MAPK activity
• chemotaxis
• response to stress
• inflammatory response
• complement activation
• complement activation, alternative pathway
• complement activation, classical pathway
• G-protein coupled receptor protein signaling pathway
• cytolysis
| Orthologs = Template:GNF Ortholog box
}} Complement component 5 is a protein involved in the complement system.
It is cleaved into C5a and C5b:
- C5a plays an important role in chemotaxis.[5]
- C5b forms the first part of the complement membrane attack complex.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000106804 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026874 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Immunology at MCG 1/phagocyt
Further reading
External links
- Complement+5 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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