Solid-phase extraction

Solid-phase extraction (SPE) is an extraction method that uses a solid phase and a liquid phase to isolate one, or one type, of analyte from a solution. It is usually used to clean up a sample before using a chromatographic or other analytical method to quantitate the amount of analyte(s) in the sample.

Method for sample purification whereby either the desired or undesired components of a mixture have preferential affinity for a solid material. Adding the mixture to the solid material then allows facile separation of the desired material by filtration.