Challenge–dechallenge–rechallenge
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Challenge-dechallenge-rechallenge is a medical testing protocol in which a medicine or drug is administered, withdrawn, then re-administered, while being monitored for adverse effects. The protocol is used when statistical testing is inappropriate due to an idiosyncratic reaction by a specific individual, or a lack of sufficient test subjects.[1] The unit of analysis is the individual. During the withdraw phase, the medication is allowed to wash out of the system.
See also
References
- ^ Breggin, Ginger Ross; Breggin, Peter Roger (1995). Talking back to Prozac: what doctors won't tell you about today's most controversial drug. New York: St. Martin's Paperbacks. ISBN 0-312-95606-1.
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