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Slow afterhyperpolarization

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Slow After Hyperpolarisation (sAHP) refers to a prolonged period of hyperpolarisation in a neuron or cardiomyocyte following an action potential or other depolarising spike. sAHPs are due to an extended potassium flux via calcium activated potassium channels (I_KCa)^[1]^[2].

References

^ P. Sah, Ca(2+)-activated K+ currents in neurones: types, physiological roles and modulation. Trends Neurosci. 19 (1996) 150-154
^ P. Sah, Channels underlying neuronal calcium-activated potassium currents. Prog. Neurobiol. 66 (2002) 345-353

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