Cobalt(II) thiocyanate
Co2+ [N≡C−S−]2
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3D model (JSmol)
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| ChemSpider | |
| ECHA InfoCard | 100.019.234 |
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PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C2CoN2S2 | |
| Molar mass | 175.098 g/mol |
| Density | 2.484 g/cm3 |
| +11,090·10−6 cm3/mol | |
| Hazards | |
| GHS labelling: | |
 
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| Warning | |
| H302, H312, H332, H410 | |
| P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P391, P501 | |
| Safety data sheet (SDS) | External MSDS |
| Related compounds | |
Other anions
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Cobalt(II) cyanate |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Cobalt(II) thiocyanate is an inorganic compound with the formula Co(SCN)2.[1] The anhydrous compound is a coordination polymer with a layered structure. The trihydrate, Co(SCN)2(H2O)3, is a isothiocyanate complex used in the cobalt thiocyanate test (or Scott test) for detecting cocaine.
Structure and preparation
[edit]2_Xray.jpg?lang=en)
The structures of Co(SCN)2 and its hydrate Co(SCN)2(H2O)3 have been determined using X-ray crystallography.[1] Co(SCN)2 forms infinite 2D sheets as in the mercury(II) thiocyanate structure type, where as Co(SCN)2(H2O)3 consists of isolated tetrahedral Co(SCN)2(H2O)2 centers and one equivalent of water of crystallization.[2]
The hydrate may be prepared by the salt metathesis reactions, such as the reaction of aqueous cobalt(II) sulfate and barium thiocyanate to produce a barium sulfate precipitate, leaving the hydrate of Co(SCN)2 in solution:[2]
- CoSO4 + Ba(SCN)2 → BaSO4 + Co(SCN)2
or the reaction of the hexakisacetonitrile cobalt(II) tetrafluoroborate and potassium thiocyanate, precipitating KBF4
- [Co(NCMe)6](BF4)2 + 2KSCN → 2KBF4 + Co(SCN)2.
The anhydrate can then be prepared via addition of diethylether as an antisolvent.[1]
Scott's test
[edit]Scott's Test or Scott Test refers to a rapid and low-cost method of preliminary testing for cocaine.[3] It is a mixture of an acid medium and 2% cobalt(II) thiocyanate.[4] While typically used for cocaine, it will also indicate the presence of ketamine hydrochlorides, heroin, and dibucaine in amounts higher than 1 mg, as well as diltiazem and lidocaine in amounts higher than or equal to 5 mg.[5] When the cobalt thiocyanate reagent interacts with cocaine hydrochloride, the solution turns from a reddish-brown to a vibrant blue.[4]
The test has been responsible for widespread false positives and false convictions.[6][7]
Cobalt thiocyanate test
[edit]Detailed procedures for the cobalt thiocyanate test, often sold as the "morris reagent" are available. The reagent consists of 2% cobalt thiocyanate dissolved in dilute acid.[8] Glycerol is often added to stabilise the cobalt complex, ensuring it only goes blue when in contact with an analyte and not due to drying.[9]
Addition of the cobalt thiocyanate reagent to cocaine hydrochloride results in the surface of the particles turning a bright blue (faint blue for cocaine base). The solution changes back to pink upon adding some hydrochloric acid. Addition of chloroform, results in a blue organic layer for both cocaine hydrochloride and cocaine base. Diphenhydramine and lidocaine also give blue organic layers. These compounds are known false positives for cocaine. Lidocaine is commonly used to adulterate or mimic cocaine due to its local anaesthetic effect.
If the procedure is adjusted to basify the sample rather than acidifying it, the test can be used to test for ketamine hydrochloride.[10]
References
[edit]- ^ a b c Shurdha, Endrit; Lapidus, Saul H.; Stephens, Peter W.; Moore, Curtis E.; Rheingold, Arnold L.; Miller, Joel S. (2012-09-17). "Extended Network Thiocyanate- and Tetracyanoethanide-Based First-Row Transition Metal Complexes". Inorganic Chemistry. 51 (18): 9655–9665. doi:10.1021/ic300804y. ISSN 0020-1669. PMID 22928927.
- ^ a b Cano, F. H.; García-Blanco, S.; Laverat, A. G. (1976). "The crystal structure of cobalt(II) thiocyanate trihydrate". Acta Crystallographica Section B. 32 (5): 1526. doi:10.1107/S0567740876005694.
- ^ de Souza, Diego Mendes; de Moura Messias, Pedro Judah; Silva Santos, Isabella da; Ramalho, Eduardo Dias; Ferrari Júnior, Ettore; de Oliveira Morais, Pedro Augusto (2022-06-01). "Scott test associated with multivariate image analysis: A more selective alternative for cocaine research in forensic laboratories". Forensic Science International. 335: 111277. doi:10.1016/j.forsciint.2022.111277. ISSN 0379-0738.
- ^ a b "Is Scott's reagent reliable?". September 4, 2023.
{{cite web}}: CS1 maint: url-status (link) - ^ Lieberman, Marya (February 9, 2023). "How does the Scott Test for Cocaine Work?".
{{cite web}}: CS1 maint: url-status (link) - ^ Ryan Gabrielson; Topher Sanders (July 7, 2016). "Busted: Tens of thousands of people every year are sent to jail based on the results of a $2 roadside drug test. Widespread evidence shows that these tests routinely produce false positives. Why are police departments and prosecutors still using them?". ProPublica.
- ^ Ryan Gabrielson (July 11, 2016). "'No Field Test is Fail Safe': Meet the Chemist Behind Houston's Police Drug Kits". ProPublica.
- ^ Deakin, Anna (2003). "A Study of Acids Used for the Acidified Cobalt Thiocyanate Test for Cocaine Base" (PDF). Microgram Journal. 1 (1–2): 40–43. Archived from the original (PDF) on 16 March 2019.
- ^ Haddoub, Rose; Ferry, Daniel; Marsal, Philippe; Siri, Olivier (2011). "Cobalt thiocyanate reagent revisited for cocaine identification on TLC". New Journal of Chemistry. 35 (7): 1351. doi:10.1039/c1nj20234k. ISSN 1144-0546.
- ^ Morris, JA (2007). "Modified Cobalt Thiocyanate Presumptive Color Test for Ketamine Hydrochloride". J Forensic Sci. 52 (1): 84–87. doi:10.1111/j.1556-4029.2006.00331.x. PMID 17209915. S2CID 27411302.