ADB-5'F-BUTINACA

ADB-5'F-BUTINACA
Identifiers
	IUPAC name N-(1-amino-3,3-dimethyl-1-oxo-2-butanyl)-1-butyl-1H-5-fluoroindazole-3-carboxamide;
Chemical and physical data
Formula	C18H25FN4O2
Molar mass	348.422 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES NC(=O)[C@@H](NC(=O)c1nn(CCCC)c2ccc(F)cc21)C(C)(C)C;

ADB-5'F-BUTINACA is an indazole-3-carboxamide based synthetic cannabinoid receptor agonist. It was synthesised as part of investigations into related compounds such as ADB-5'Br-BUTINACA and MDMB-5'Br-BUTINACA, and confirmed that fluorination of the indazole 5-position increases potency in a similar manner to bromination.^[1]

References

^ Deventer MH, Persson M, Norman C, Liu H, Connolly MJ, Daéid NN, McKenzie C, Gréen H, Stove CP (October 2023). "In vitro cannabinoid activity profiling of generic ban-evading brominated synthetic cannabinoid receptor agonists and their analogs". Drug Testing and Analysis. doi:10.1002/dta.3592. PMID 37903509. S2CID 264671035.

[pmid37903509-1] Deventer MH, Persson M, Norman C, Liu H, Connolly MJ, Daéid NN, McKenzie C, Gréen H, Stove CP (October 2023). "In vitro cannabinoid activity profiling of generic ban-evading brominated synthetic cannabinoid receptor agonists and their analogs". Drug Testing and Analysis. doi:10.1002/dta.3592. PMID 37903509. S2CID 264671035.

[1]

See also

References