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Quantitative insulin sensitivity check index

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This is an old revision of this page, as edited by A455bcd9 (talk | contribs) at 18:17, 8 August 2023 (Found a source. The 0.45 limit seems to be total BS.). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

The quantitative insulin sensitivity check index (QUICKI) is derived using the inverse of the sum of the logarithms of the fasting insulin and fasting glucose:

1 / (log(fasting insulin μU/mL) + log(fasting glucose mg/dL))

This index correlates well with glucose clamp studies (r = 0.78), and is useful for measuring insulin sensitivity (IS), which is the inverse of insulin resistance (IR). It has the advantage of that it can be obtained from a fasting blood sample, and is the preferred method for certain types of clinical research.

Healthy persons have a QUICKI index above 0.357.[1]

See also

Sources

  • Katz, Arie; Nambi, Sridhar S.; Mather, Kieren; Baron, Alain D.; Follmann, Dean A.; Sullivan, Gail; Quon, Michael J. (2000-07-01). "Quantitative Insulin Sensitivity Check Index: A Simple, Accurate Method for Assessing Insulin Sensitivity In Humans". The Journal of Clinical Endocrinology & Metabolism. 85 (7): 2402–2410. doi:10.1210/jcem.85.7.6661. ISSN 0021-972X. PMID 10902785.
  • Source as above - Katz et al. Also data for unusually healthy individuals derived from those practicing caloric restriction. See CR Society for details.
  1. ^ Hřebíček, Jiří; Janout, Vladimír; Malinčíková, Jana; Horáková, Dagmar; Čížek, Luděk (2002-01-01). "Detection of Insulin Resistance by Simple Quantitative Insulin Sensitivity Check Index QUICKI for Epidemiological Assessment and Prevention". The Journal of Clinical Endocrinology & Metabolism. 87 (1): 144–144. doi:10.1210/jcem.87.1.8292. ISSN 0021-972X.