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This is an old revision of this page, as edited by WikiEd97531 (talk | contribs) at 20:39, 31 May 2023 ("high-potency probiotic": Reply). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.
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This article was accepted from this draft on 17 July 2022 by reviewer Timtrent (talk · contribs).
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Prior content in this draft duplicated one or more previously published sources. The material was copied from: https://cdn.shopify.com/s/files/1/0736/3645/files/ExeGi_Pharma_VSL_White_Paper_Design_FINAL_PAGES.pdf?2990 https://www.businesswire.com/news/home/20181126005445/en/Maryland-Federal-Jury-Unanimously-Finds-Probiotic-Sellers-Liable-for-False-Advertising-and-Awards-Product-Inventor-More-than-18-Million-in-Damages. Copied or closely paraphrased material has been rewritten or removed and must not be restored, unless it is duly released under a compatible license. (For more information, please see "using copyrighted works from others" if you are not the copyright holder of this material, or "donating copyrighted materials" if you are.)

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POV

This article seems to promote rather inform PROFESSOR De Simone, currently only clinical trials are running with more or less success. Hence, without proper use of reliable sources acc. to WP:MEDRS, this is subject to deletion. --Julius Senegal (talk) 18:36, 22 January 2023 (UTC)[reply]

I am trying to evolve the page entry that I opened while in hospital after losing an organ and was at risk for losing more bowel. Your posts are strangely aggressive and you labeled this a promotion for the professor who invented it, which I find odd every time I see the flag. The page title is the therapy/treatment and I included him because I feel it is relevant to know if a medical doctor developed it. In the IBD space, patients will know that for surgery one pouch surgery option is called a Koch pouch after its doctor inventor. Another is the Parks' pouch after its inventor. Parks also has other surgical treatments named after him including "Parks' painless proctoplasty". Another example is the Hegar dilator which people who have had rectal surgery might be prescribed after surgery named after German doctor Hegar. In my opinion, this is no different. Further, I can't understand why you are so against this entry and come across as an assuming sniper rather than a collaborator who wants to evolve entries for info to help people.(Personal attack removed) WikiEd97531 (talk) 12:57, 9 February 2023 (UTC)[reply]
Please stick to our rules, like WP:PROMO. If De Simone is relevant for this encyclopedia, then you are free to write an own article about him.
Please take WP:MEDRS into account. What we need are reliable secondary sources.
Please don't use sources which do not cover statements.
If you continue with violating WP:PA, this will have consequences. --Julius Senegal (talk) 14:11, 9 February 2023 (UTC)[reply]

"high-potency probiotic"

What does that mean, really? Sounds like marketing speech. Gråbergs Gråa Sång (talk) 08:46, 30 May 2023 (UTC)[reply]

It's not marketing speech. I had originally put this in the first draft I wrote to explain what it is classified as but it was removed by Julius: "The probiotic formulation is classed as a high potency probiotic medical food in the United States. It is intended for the dietary management of dysbiosis (microbiota imbalance) associated with irritable bowel syndrome (IBS), antibiotic-associated diarrhea, ulcerative colitis (UC), pouchitis, hepatic encephalopathy (HE), pregnancy, for babies born by Caesarean Section (C-section), and for babies that are bottle-fed." Then, I tried to explain by using the US FDA guidelines but Julius removed that to: "The probiotic formulation is classed as a probiotic medical food in the United States according to the Food and Drug Administration's Federal Food, Drug, and Cosmetic Act."
With all that failing, I then found in a Forbes article, because you said to not use primary sources, that it is a 'high potency' probiotic.
The importance of "medical food" grade or "high potency" is that it I'm trying to explain that it is not your typical store bought probiotic and people should NOT take it!
If you look at other therapies used for the medical management of ulcerative colitis, for example, they all explain what the 'therapy' is classed as: infliximab classed as biologic:
https://en.wikipedia.org/wiki/Infliximab
Mesalazine is classed as 5-ASA: https://en.wikipedia.org/wiki/Mesalazine
I only used the Forbes link because Julius took the other links out.
If you look here at a recent guidelines on probiotics 'high potency' is relevant for people using things as a medical therapy (typically requires high potency and medical food status) vs the general public who typically SHOULD NOT use these higher dosage products. It is important - it isn't marketing, I am trying to explain what exactly this is and I'm only getting snipped with sarcastic comments that rip-down instead of work together and evolve into a helpful entry.
International Scientific Association for Probiotics and Prebiotics (ISAPP)
https://www.tandfonline.com/doi/full/10.1080/19490976.2023.2185034
In fact there are a not of news articles about those guidelines when I Google just now including one that looks like it was co-authored by a medical team at Basal hospital and the inventor of the De Simone Formulation:
Portugal to English: https://www.medscape.com/viewarticle/992453
https://www.wholefoodsmagazine.com/articles/8758-isapp-defines-postbiotic-stratum-outlines-ingredient-benefits
https://medicalxpress.com/news/2023-05-resource-gastroenterologists-probiotics-prebiotics-clinical.html
and
https://medicalxpress.com/news/2023-05-disrupted-gut-microbiome-involved-depression.html
I almost bought the other probiotic for disease management when I was in intestinal failure, as I already explained which is why I opened this page. Too many people confused. Snarky comments that don't add value aren't helping. I had found online that there is a big class action lawsuit in the USA because of the mismarketing of the probiotics. I am not involved, thankfully, I figured out the change and didn't buy it but other people say they were harmed in some way. They couldn't find the info. They didn't understand.
https://www.classaction.org/news/class-action-accuses-pharma-companies-of-secretly-reformulating-vsl3-probiotics-product#:~:text=According%20to%20the%20lawsuit%2C%20De,and%20thereby%20increase%20profit%20margins.
Now, without the time wasting snipping and sarcastic comments that are unprofessional, what exact sort of source do you need to clarify what level of probiotic product this is?
I would like to revert to the original language that it is classed as a medical food by the US FDA. What exactly do you need to see in writing? I'm asking for help, not a public mobbing. WikiEd97531 (talk) 20:39, 31 May 2023 (UTC)[reply]

Also, can this [1] be considered the official website of the whatever? Gråbergs Gråa Sång (talk) 08:47, 30 May 2023 (UTC)[reply]

Reverting POV