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Forster–Decker method

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Overall Reaction

The Forster–Decker Method is a series of chemical reactions that transform a primary amine (1) ultimately to a secondary amine (6).[1][2] The first step is the formation of a Schiff base (3), followed by alkylation, and hydrolysis.

The Forster-Decker method
The Forster-Decker method

Mechanism

The first step in the Forster-Decker Method is the formation of an imine (Schiff base) from a primary amine.

See also

References

  1. ^ Forster, Martin Onslow (1899). "XCI.–Influence of substitution on specific rotation in the bornylamine series". Journal of the Chemical Society, Transactions. 75: 934–935. doi:10.1039/CT8997500934.
  2. ^ Decker, H.; Becker, P. Ann. 1913, 395, 362.


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