Biomolecular Object Network Databank

Unleashed Informatics

The Blueprint Initiative started as a research program in the lab of Dr. Christopher Hogue the Samuel Lunenfeld Research Institute at Mount Sinai in Toronto. On December 14, 2005 Unleashed Informatics Limited acquired the commercial rights to The Blueprint Initiative intellectual property. This included rights to the protein interaction database BIND, the small molecule interaction database SMID, as well as the data warehouse SeqHound. Unleashed Informatics is a data management service provider and is overseeing the management and curation of The Blueprint Initiative under the guidance of Dr. Hogue[1].

Unleashed Informatics has created a novel resource, the Biomolecular Object Network Database (BOND), which integrates the original blueprint initiative databases as well as other databases, such as Genbank, combined with many tools required to analyze these data. Annotations links for sequences, including taxon identifiers, redundant sequences, Genome Ontology descriptions, Online Mendelian Inheritance in Man identifiers, conserved domains, data base cross-references, LocusLink Identifiers and complete genomes are also available. Bond facilitates cross-database queries and is the first open access resource which integrates interaction and sequence data[2].

Unleashed Informatics also hosts the Small Molecule Interaction Database (SMID). Open access versions of BOND and SMID are available at http://www.unleashedinformatics.com/index.php?pg=products. Commercial versions, BONDplus and SMIDsuiteplus, are also available which provide additional data and bioinformatics support.

User Statistics

The number of Unleashed Registrants has increased 10 fold since the integration of BIND. As of December 2006 registration fell just short of 10,000. Subscribers to the commercial versions of BOND fall into six general categories; agriculture and food, biotech, pharmaceuticals, informatics, materials and other. The biotechnology sector is the largest of these groups, holding 28% of subscriptions. Pharmaceuticals and informatics follow with 22% and 18% respectively. The United States holds the bulk of these subscriptions, 69%. Other countries with access to the commercial versions of BOND include Canada, the United Kingdom, Japan, China, Korea, Germany, France, India and Australia. All of these countries fall below 6% in user share[2].

1. www.blueprint.org 2. bond.unleashedinformatics.com