Storiform pattern
A storiform, cartwheel or whorled pattern is a sign in histopathology. Microscopically, storiform arrangements appear to have center points that radiate cells or connective tissue outward. Storiform patterns may be irregular and, at lower magnification, can cause tissue to appear tangled into clumps.[1] The name "storiform" originates from Latin storea (woven), as storiform tissue tends to resemble woven fabric on microscopy.
Skin tumors that can be classified as "storiform," having spindle cells with elongated nuclei radiating from a center point, are mainly:[2]
- Fibrous histiocytoma (dermatofibroma)
- Soft tissue perineurioma
- Dermatofibrosarcoma protuberans
A histologic sign of IgG4-related disease is storiform fibrosis, accompanied by a dense lymphoplasmocytic infiltrate and often a partially eosinophilic infiltrate, and obliterative phlebitis.[1][3]
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Dermatofibrosarcoma protuberans. HE stain. -
A collagenoma, having a cartwheel or woven appearance.
References
- ^ a b Stone, John H.; Zen, Yoh; Deshpande, Vikram (2012). "IgG4-Related Disease". The New England Journal of Medicine. 366: 539–551. doi:10.1056/NEJMra1104650.
- ^ Choi, Joon Hyuk; Ro, Jae Y. (2018). "Cutaneous Spindle Cell Neoplasms: Pattern-Based Diagnostic Approach". Archives of Pathology & Laboratory Medicine. 142 (8): 958–972. doi:10.5858/arpa.2018-0112-RA. ISSN 0003-9985. PMID 30040457.
- ^ Deshpande, Vikram; Zen, Yoh; Chan, John K.C.; et al. (2012). "Consensus statement on the pathology of IgG4-related disease". Modern Pathology (25): 1181–1192. doi:10.1038/modpathol.2012.72.
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