nQuery Sample Size Software
 | This article contains promotional content. (May 2018) |
nQuery is a clinical trial design platform used for the design and monitoring of adaptive, group sequential and fixed sample size trials. It is most commonly used by biostatisticians to calculate sample size and statistical power for adaptive clinical trial design. nQuery is a proprietary software developed and distributed by Statsols. The software includes calculations for 1000+ sample sizes and power scenarios.
nQuery history
Janet Dixon Elashoff is a now-retired American statistician and daughter of the mathematician and statistician, Wilfrid Joseph Dixon, creator of BMDP. J. Elashoff is also the retired Director of the Division of Biostatistics, Cedars-Sinai Medical Center. While at UCLA and Cedars-Sinai during the 1990s, she wrote the program nQuery Sample Size Software (named nQuery Advisor back then). This software quickly became widely used to estimate the sample size requirements for pharmaceutical trials. She joined the company, Statistical Solutions LLC, to commercialize it.[1]
nQuery featured in scientific journals
| This article contains promotional content. (November 2021) |
As of May 2022, there are 8,250 published scientific studies, which are available to the public through Google Scholar, that feature nQuery. The U.S. National Institutes of Health Library lists over 895 published studies that utilized nQuery for sample size calculation during clinical trial design.
Frequentist and Bayesian statistics
nQuery allows researchers to apply both frequentist and Bayesian statistics to calculate the appropriate sample size for their study.[2]
Adaptive clinical trial design
nQuery is used for adaptive clinical trial design. Trials with an adaptive design are often reported to be more efficient, informative, and ethical than trials with a traditional fixed design since they conserve resources such as time and money, and most of time, require fewer participants.[3]
nQuery acquired by Insightful Science
In June 2020, nQuery was acquired by Insightful Science.[4]
References
- ^ Chernick, Michael R.; Friis, Robert H. (2003), Introductory Biostatistics for the Health Sciences: Modern Applications Including Bootstrap, Wiley series in probability and statistics, John Wiley & Sons, p. 360, ISBN 9780471458654
- ^ "What sample size and power analysis procedures you get in nQuery | Sample Size Software | Power Analysis Software".
- ^ Pallmann, Philip; Bedding, Alun W.; Choodari-Oskooei, Babak; Dimairo, Munyaradzi; Flight, Laura; Hampson, Lisa V.; Holmes, Jane; Mander, Adrian P.; Odondi, Lang'o; Sydes, Matthew R.; Villar, Sofía S.; Wason, James M. S.; Weir, Christopher J.; Wheeler, Graham M.; Yap, Christina; Jaki, Thomas (2018). "Adaptive designs in clinical trials: Why use them, and how to run and report them". BMC Medicine. 16 (1): 29. doi:10.1186/s12916-018-1017-7. PMC 5830330. PMID 29490655.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ "Insightful Science Acquires nQuery, Builds on Portfolio of Category-Leading Scientific Software Solutions".