Mustard Database
| Content | |
|---|---|
| Description | Contains AR determinants and curated AR genes identified from metagenomics |
| Data types captured | Antimicrobial resistance genes and AR Determinants |
| Organisms | Bacteria |
| Contact | |
| Primary citation | PMID 30478291 |
| Access | |
| Website | mgps |
| Download URL | Download |
| Miscellaneous | |
| Bookmarkable entities | yes |
Mustard is a database of Antimicrobial Resistance Determinants (ARDs) from the Human gut microbiome. MUSTARD tracked resistance genes in the Metahit catalog using Protein homology modelling with Pairwise Comparative Modelling (PCM). This approach increased prediction specificity, especially for distant related protein homologues.[1] Using PCM, 6095 ARDs from 20 families in the human gut microbiota. Mustard was compared to other antibiotic resistance databases likeResFinder,[2] ARG-ANNOT,[3].[4][5][6]
See also
References
- ^ Ehrlich, S. Dusko; Kennedy, Sean P.; Doré, Joël; Haimet, Florence; Weiszer, Kevin; Levenez, Florence; Letur, Aline; Léjard, Véronique; Léonard, Pierre (January 2019). "Prediction of the intestinal resistome by a three-dimensional structure-based method" (PDF). Nature Microbiology. 4 (1): 112–123. doi:10.1038/s41564-018-0292-6. ISSN 2058-5276. PMID 30478291. S2CID 53757858.
- ^ Zankari, E.; Hasman, H.; Cosentino, S.; Vestergaard, M.; Rasmussen, S.; Lund, O.; Aarestrup, F. M.; Larsen, M. V. (2012-07-10). "Identification of acquired antimicrobial resistance genes". Journal of Antimicrobial Chemotherapy. 67 (11): 2640–2644. doi:10.1093/jac/dks261. ISSN 0305-7453. PMC 3468078. PMID 22782487.
- ^ Gupta, Sushim Kumar; Padmanabhan, Babu Roshan; Diene, Seydina M.; Lopez-Rojas, Rafael; Kempf, Marie; Landraud, Luce; Rolain, Jean-Marc (2013-10-21). "ARG-ANNOT, a New Bioinformatic Tool To Discover Antibiotic Resistance Genes in Bacterial Genomes". Antimicrobial Agents and Chemotherapy. 58 (1): 212–220. doi:10.1128/aac.01310-13. ISSN 0066-4804. PMC 3910750. PMID 24145532.
- ^ Allen, Heather K; Moe, Luke A; Rodbumrer, Jitsupang; Gaarder, Andra; Handelsman, Jo (2008-10-09). "Functional metagenomics reveals diverse β-lactamases in a remote Alaskan soil". The ISME Journal. 3 (2): 243–251. doi:10.1038/ismej.2008.86. ISSN 1751-7362. PMID 18843302. S2CID 16496336.
- ^ Moore, Aimée M.; Patel, Sanket; Forsberg, Kevin J.; Wang, Bin; Bentley, Gayle; Razia, Yasmin; Qin, Xuan; Tarr, Phillip I.; Dantas, Gautam (2013-11-13). "Pediatric Fecal Microbiota Harbor Diverse and Novel Antibiotic Resistance Genes". PLOS ONE. 8 (11): e78822. doi:10.1371/journal.pone.0078822. ISSN 1932-6203. PMID 24236055.
- ^ Sommer, M. O. A.; Dantas, G.; Church, G. M. (2009-08-27). "Functional Characterization of the Antibiotic Resistance Reservoir in the Human Microflora". Science. 325 (5944): 1128–1131. doi:10.1126/science.1176950. ISSN 0036-8075. PMC 4720503. PMID 19713526.
 | This Biological database-related article is a stub. You can help Wikipedia by expanding it. |