Module talk:Infobox gene/testcases 2

AIF1

Module:Infobox gene →

AIF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2D58, 2G2B
Identifiers
Aliases	AIF1, AIF-1, IBA1, IRT-1, IRT1, allograft inflammatory factor 1, Iba-1
External IDs	OMIM: 601833; MGI: 1343098; HomoloGene: 1226; GeneCards: AIF1; OMA:AIF1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p21.33 Start 31,615,217 bp End 31,617,021 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17 B1|17 18.59 cM Start 35,389,967 bp End 35,395,044 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte granulocyte bone marrow cells testicle right lung gallbladder C1 segment rectum spleen right coronary artery Top expressed in seminiferous tubule mesenteric lymph nodes spermatid spleen stroma of bone marrow thymus spermatocyte subcutaneous adipose tissue optic nerve aortic valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding metal ion binding actin filament binding actin binding molecular function Cellular component cytoplasm cytosol perikaryon cell projection membrane ruffle plasma membrane ruffle membrane actin filament perinuclear region of cytoplasm phagocytic cup cytoskeleton nucleus lamellipodium Biological process cellular response to extracellular stimulus positive regulation of smooth muscle cell chemotaxis response to cytokine positive regulation of protein phosphorylation negative regulation of smooth muscle cell proliferation positive regulation of cell migration positive regulation of muscle hyperplasia positive regulation of nitric oxide biosynthetic process positive regulation of monocyte chemotaxis negative regulation of apoptotic process response to glucocorticoid response to electrical stimulus negative regulation of gene expression cellular response to hydroperoxide actin filament bundle assembly microglial cell activation positive regulation of G1/S transition of mitotic cell cycle actin filament polymerization negative regulation of smooth muscle cell chemotaxis cellular response to hormone stimulus phagocytosis, engulfment response to axon injury positive regulation of T cell proliferation cellular response to interferon-gamma cellular response to morphine Rac protein signal transduction inflammatory response ruffle assembly positive regulation of T cell migration positive regulation of smooth muscle cell proliferation cerebellum development positive regulation of cell population proliferation regulation of gene expression parallel actin filament bundle assembly cellular response to oxidative stress positive regulation of chemotaxis actin crosslink formation positive regulation of mononuclear cell migration positive regulation of fibroblast growth factor production Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 199 11629 Ensembl ENSG00000206428 ENSG00000235985 ENSG00000235588 ENSG00000234836 ENSG00000237727 ENSG00000204472 ENSMUSG00000024397 UniProt P55008 Q4V347 O70200 RefSeq (mRNA) NM_001623 NM_004847 NM_032955 NM_001318970 NM_019467 NM_001361501 NM_001361502 RefSeq (protein) NP_001305899 NP_001614 NP_116573 NP_001614.3 NP_062340 NP_001348430 NP_001348431 Location (UCSC) Chr 6: 31.62 – 31.62 Mb Chr 17: 35.39 – 35.4 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Module:Infobox gene/sandbox →

AIF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2D58, 2G2B
Identifiers
Aliases	AIF1, AIF-1, IBA1, IRT-1, IRT1, allograft inflammatory factor 1, Iba-1
External IDs	OMIM: 601833; MGI: 1343098; HomoloGene: 1226; GeneCards: AIF1; OMA:AIF1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p21.33 Start 31,615,217 bp End 31,617,021 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17 B1|17 18.59 cM Start 35,389,967 bp End 35,395,044 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte granulocyte bone marrow cells testicle right lung gallbladder C1 segment rectum spleen right coronary artery Top expressed in seminiferous tubule mesenteric lymph nodes spermatid spleen stroma of bone marrow thymus spermatocyte subcutaneous adipose tissue optic nerve aortic valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding metal ion binding actin filament binding actin binding molecular function Cellular component cytoplasm cytosol perikaryon cell projection membrane ruffle plasma membrane ruffle membrane actin filament perinuclear region of cytoplasm phagocytic cup cytoskeleton nucleus lamellipodium Biological process cellular response to extracellular stimulus positive regulation of smooth muscle cell chemotaxis response to cytokine positive regulation of protein phosphorylation negative regulation of smooth muscle cell proliferation positive regulation of cell migration positive regulation of muscle hyperplasia positive regulation of nitric oxide biosynthetic process positive regulation of monocyte chemotaxis negative regulation of apoptotic process response to glucocorticoid response to electrical stimulus negative regulation of gene expression cellular response to hydroperoxide actin filament bundle assembly microglial cell activation positive regulation of G1/S transition of mitotic cell cycle actin filament polymerization negative regulation of smooth muscle cell chemotaxis cellular response to hormone stimulus phagocytosis, engulfment response to axon injury positive regulation of T cell proliferation cellular response to interferon-gamma cellular response to morphine Rac protein signal transduction inflammatory response ruffle assembly positive regulation of T cell migration positive regulation of smooth muscle cell proliferation cerebellum development positive regulation of cell population proliferation regulation of gene expression parallel actin filament bundle assembly cellular response to oxidative stress positive regulation of chemotaxis actin crosslink formation positive regulation of mononuclear cell migration positive regulation of fibroblast growth factor production Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 199 11629 Ensembl ENSG00000206428 ENSG00000235985 ENSG00000235588 ENSG00000234836 ENSG00000237727 ENSG00000204472 ENSMUSG00000024397 UniProt P55008 Q4V347 O70200 RefSeq (mRNA) NM_001623 NM_004847 NM_032955 NM_001318970 NM_019467 NM_001361501 NM_001361502 RefSeq (protein) NP_001305899 NP_001614 NP_116573 NP_001614.3 NP_062340 NP_001348430 NP_001348431 Location (UCSC) Chr 6: 31.62 – 31.62 Mb Chr 17: 35.39 – 35.4 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse