https://de.wikipedia.org/w/api.php?action=feedcontributions&feedformat=atom&user=SlothMcCarty 2025-05-08T21:52:13Z Benutzerbeiträge MediaWiki 1.44.0-wmf.28 https://de.wikipedia.org/w/index.php?title=Lipotropin&diff=79265353 2009-10-07T17:42:39Z

<p>SlothMcCarty: +POMC infobox</p> <hr /> <div>{{protein<br /> | Name = proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)<br /> | caption = {{POMC}}<br /> | image = <br /> | width = <br /> | HGNCid = 9201<br /> | Symbol = POMC<br /> | AltSymbols = <br /> | EntrezGene = 5443<br /> | OMIM = 176830<br /> | RefSeq = NM_000939<br /> | UniProt = P01189<br /> | PDB = <br /> | ECnumber = <br /> | Chromosome = 2<br /> | Arm = p<br /> | Band = 23<br /> | LocusSupplementaryData = <br /> }}<br /> <br /> '''Lipotropin''' is a [[hormone]] produced by the cleavage of [[pro-opiomelanocortin]] (POMC). The [[anterior pituitary|anterior pituitary gland]] produces the [[pro-hormone]] POMC, which undergoes cleavage to [[Adrenocorticotropic hormone|adrenocorticotropin]] (ACTH) and β-lipotropin (β-LPH).<br /> <br /> == β-Lipotropin ==<br /> <br /> β-lipotropin is a 90 [[amino acid]] [[polypeptide]] that is the [[C-terminus|carboxy-terminal]] fragment of POMC.<br /> <br /> It stimulates [[melanocytes]] to produce [[melanin]], and can also be cleaved into smaller peptides. In humans, γ-lipotropin, [[α-MSH]], [[β-MSH]], [[γ-MSH]], [[α-endorphin]], [[β-endorphin]], [[γ-endorphin]], and [[met-enkephalin]] are all possible fragments of β-lipotropin.&lt;ref&gt;{{citation | url=http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=346829&amp;blobtype=pdf | title= NH2-Terminal amino acid sequence and peptide mapping of purified human β-lipotropin: Comparison with previously proposed sequences |author= Joachim Spiess, Charles D. Mount, Wendell E. Nicholson, David N. Orth | journal= Proc. Natl. Acad. Sci. USA | page= 5071-5 |volume= 79 |year= 1982 |accessdate= 2007-06-21}}&lt;/ref&gt;<br /> <br /> β-lipotropin also performs lipid-mobilizing functions such as [[lipolysis]] and [[steroidogenesis]].<br /> <br /> == γ-Lipotropin ==<br /> <br /> γ-lipotropin is the [[N-terminus|amino-terminal]] peptide fragment of β-lipotropin. In humans, it has 56 amino acids.<br /> <br /> == References ==<br /> {{Reflist|2}}<br /> <br /> == External links ==<br /> * {{MeshName|beta-Lipotropin}}<br /> * {{MeshName|gamma-Lipotropin}}<br /> <br /> <br /> {{Hormones}}<br /> {{Neuropeptides}}<br /> {{Neurotransmitters}}<br /> <br /> <br /> {{biology-stub}}<br /> <br /> [[dv:ލައިޕޯޓްރޮޕިން]]</div>

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