https://de.wikipedia.org/w/api.php?action=feedcontributions&feedformat=atom&user=CocoapunkWikipedia - Benutzerbeiträge [de]2025-05-29T23:35:18ZBenutzerbeiträgeMediaWiki 1.45.0-wmf.3https://de.wikipedia.org/w/index.php?title=Natriumthiopental&diff=203240049Natriumthiopental2004-11-16T01:54:44Z<p>Cocoapunk: </p>
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<div>'''Sodium thiopental''' (also called '''sodium pentothal''' (&trade; of Abbott Laboratories), '''thiopental''' (or '''thiopentone''') '''sodium''') is a rapid-onset, short-acting [[barbiturate]] [[general anesthetic]].<br />
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It induces [[general anaesthesia]] within 60 seconds of [[intravenous injection]] and lasts around 10-30 minutes. Up until fairly recently it was the most popular anesthetic induction agent in many parts of the world. However, in recent years it has been overtaken by [[propofol]], particularly for [[day surgery]].<br />
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Thiopental has no [[analgesic]] effects so it is only used as a single agent for brief procedures. More commonly, it is used to induce anesthesia prior to the use of other anesthetic agents. It is also a neuroprotective agent and was used in [[narcotherapy]]. <br />
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As with nearly all [[anaesthetic drug]]s, thiopental causes cardiovascular and respiratory depression resulting in [[hypotension]], [[apnea]] and [[airway obstruction]]. For these reasons, only [[anesthesiologist]]s and other suitably trained [[physician|doctors]] should give thiopental in an environment suitably equipped to deal with these effects. Side effects include head ache, emergence delirium, prolonged somnolence and nausea. The hangover effects may last up to 36 hours.<br />
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[[image:thiopentalsodium.png|right|chemical structure of thiopental sodium]]<br />
Its structural name is sodium 5-ethyl-5-(1-methylbutyl)-2-thiobarbiturate, empirically it is NaSC<SUB>11</SUB>H<SUB>17</SUB>O<SUB>2</SUB>N<SUB>2</SUB>. It was discovered in 1936 by Ernest H. Volwiler and Donalee L. Tabern, working for Abbott Laboratories. It was famously associated with a number of anaesthetic deaths in victims of the [[Pearl Harbor]] invasion. These deaths, relatively soon after its discovery, were due to excessive doses given to [[shock]]ed trauma patients.<br />
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Along with [[pancuronium bromide]] and [[potassium chloride]] thiopental is used in some States of the [[United States|US]] as part of the [[lethal injection]]. In the past it was claimed as a [[truth drug]].<br />
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== External links ==<br />
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* [http://www.scienceweb.org/tv/highincident.html Scienceweb.org: Sodium Pentothal]<br />
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[[Category:Anesthetics]]<br />
[[Category:Barbiturates]]<br />
[[Category:Lethal injection]]</div>Cocoapunk