https://de.wikipedia.org/w/api.php?action=feedcontributions&feedformat=atom&user=AppliedStatistics Wikipedia - Benutzerbeiträge [de] 2025-04-29T09:27:07Z Benutzerbeiträge MediaWiki 1.44.0-wmf.25 https://de.wikipedia.org/w/index.php?title=John_Ioannidis&diff=163728361 John Ioannidis 2015-10-25T03:18:16Z <p>AppliedStatistics: </p> <hr /> <div>{{Infobox scientist<br /> | name = John P. A. Ioannidis<br /> | image = &lt;!--(filename only, i.e. without &quot;File:&quot; prefix)--&gt;<br /> | image_size = <br /> | alt = <br /> | caption = <br /> | birth_date = {{birth date and age |1965|8|21|mf=y}}<br /> | birth_place = <br /> | death_date = <br /> | death_place = <br /> | death_cause = <br /> | nationality = [[Greek American]]<br /> | fields = [[Medicine]]<br /> | workplaces = [[Stanford School of Medicine]]<br /> | alma_mater = [[University of Athens Medical School]]&lt;br&gt;[[Athens College]]<br /> | doctoral_advisor = &lt;!--(or | doctoral_advisors = )--&gt;<br /> | academic_advisors = <br /> | doctoral_students = <br /> | notable_students = <br /> | known_for = <br /> | influences = <br /> | influenced = <br /> | awards = <br /> }}<br /> <br /> '''John P. A. Ioannidis''' (born August 21, 1965, in New York City) is a Professor of Medicine and of Health Research and Policy at [[Stanford University School of Medicine]] and a Professor of Statistics at Stanford University School of Humanities and Sciences. He is director of the Stanford Prevention Research Center, and co-director, along with [[Steven N. Goodman]], of the [[Meta-Research Innovation Center at Stanford]] (METRICS).&lt;ref&gt;{{cite web|url=https://med.stanford.edu/profiles/john-ioannidis|title = John P. A. Ioannidis|publisher = [[Stanford School of Medicine]] CAP Profiles|accessdate = May 24, 2014}}&lt;/ref&gt;&lt;ref&gt;{{cite web|url=http://prevention.stanford.edu/|title = Prevention Research Center |publisher= [[Stanford School of Medicine]]|accessdate = May 24, 2014}}&lt;/ref&gt; He was chairman at the Department of Hygiene and Epidemiology, [[University of Ioannina]] School of Medicine as well as [[adjunct professor]] at [[Tufts University School of Medicine]].&lt;ref&gt;{{Cite web<br /> | title = John P. A. Ioannidis<br /> | url = http://users.uoi.gr/hyepilab/people.php<br /> | publisher = Department of Hygiene and Epidemiology, [[University of Ioannina School of Medicine]]<br /> | accessdate = 2008-12-31<br /> }}&lt;/ref&gt;&lt;ref&gt;{{cite web<br /> |last=Ioannidis<br /> |first=John P.A.<br /> |title=Curriculum Vitae<br /> |url=http://www.dhe.med.uoi.gr/data/cv/CV102010D.pdf<br /> |accessdate=4 November 2010<br /> }}&lt;/ref&gt; He is best known for his research and published papers on scientific studies, particularly the 2005 paper &quot;Why Most Published Research Findings Are False&quot;.&lt;ref&gt;{{Cite journal|title = Why Most Published Research Findings Are False|url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182327/|journal = PLoS Medicine|date = 2005-08-01|issn = 1549-1277|pmc = 1182327|pmid = 16060722|volume = 2|issue = 8|doi = 10.1371/journal.pmed.0020124|first = John P. A.|last = Ioannidis}}&lt;/ref&gt; Ioannidis is one of the most-cited scientists across the scientific literature, especially in the fields of clinical medicine and social sciences, according to Thomson Reuters' Highly Cited Researchers 2015.&lt;ref&gt;{{Cite web|title = Home {{!}} Highly Cited Researchers|url = http://highlycited.com/|website = Highly Cited Researchers|accessdate = 2015-09-17}}&lt;/ref&gt;<br /> <br /> ==Biography==<br /> [[File:Ioannidis (2005) Why Most Published Research Findings Are False..pdf|thumb|Ioannidis (2005) Why Most Published Research Findings Are False.&lt;ref name=Ioannidis2005/&gt;]]<br /> Born in New York City in 1965, Ioannidis was raised in [[Athens]], [[Greece]].&lt;ref&gt;[http://www.hsph.harvard.edu/john-ioannidis/ John Ioannidis] Harvard School of Public Health&lt;/ref&gt; He was [[Valedictorian]] of his class at [[Athens College]], graduating in 1984. He also graduated first in his class at the [[University of Athens Medical School]], then attended [[Harvard University]] for his [[medical residency]] in [[internal medicine]]. He did a [[fellowship (medicine)|fellowship]] at [[Tufts University]] for [[infectious disease]]&lt;ref name=wrong&gt;{{cite book |author=[[David H. Freedman]] |coauthors= |title=Wrong: Why Experts Keep Failing Us|year=2010 |publisher=[[Little, Brown and Company]] |page= |quote=Born in 1965 in the United States to parents who were both physicians, he was raised in Athens, where he showed unusual aptitude in mathematics and snagged Greece's top student math prize. ... |url=http://books.google.com/books?id=XS4TQgAACAAJ&amp;dq |isbn=0-316-02378-7 }}&lt;/ref&gt; and came to Stanford in 2010.<br /> <br /> ===Press Coverage===<br /> The Atlantic wrote a lengthy piece on Ioannidis in 2010.&lt;ref&gt;{{cite magazine |author=[[David H. Freedman]]|title=&quot;Lies, damned lies, and medical science.&quot; |publisher=[[The Atlantic]]|page= 306.4 (2010): 76-84.|url=http://www.theatlantic.com/magazine/archive/2010/11/lies-damned-lies-and-medical-science/308269/}}&lt;/ref&gt;&lt;br&gt;<br /> <br /> The Economist wrote a shorter piece on Ioannidis in 2014 about the foundation, with [[Steven Goodman]], of the [[Meta-Research Innovation Centre]] at [[Stanford University]].&lt;ref&gt;{{cite magazine |title=&quot;Combating bad science: Metaphysicians&quot;|publisher=[[The Economist]]|url=http://www.economist.com/news/science-and-technology/21598944-sloppy-researchers-beware-new-institute-has-you-its-sights-metaphysicians/}}&lt;/ref&gt;<br /> <br /> ==Research findings==<br /> <br /> Ioannidis's 2005 paper &quot;Why Most Published Research Findings Are False&quot;&lt;ref name=Ioannidis2005&gt;{{Cite journal | last1 = Ioannidis | first1 = J. P. A. | authorlink1 = John P. A. Ioannidis| title = Why Most Published Research Findings Are False | journal = PLoS Medicine | volume = 2 | issue = 8 | pages = e124 | year = 2005 | pmid = 16060722 | pmc = 1182327 | doi = 10.1371/journal.pmed.0020124}}&lt;/ref&gt; has been the most downloaded technical paper from the journal ''[[PLoS Medicine]]''.&lt;ref&gt;{{Cite news<br /> | author = [[Robert Lee Hotz]]<br /> | title = Most Science Studies Appear to Be Tainted By Sloppy Analysis<br /> | url = http://online.wsj.com/public/article_print/SB118972683557627104.html<br /> | work = Science Journal WSJ.com<br /> | publisher = Dow Jones &amp; Company<br /> | date = 2007-09-14<br /> }}&lt;/ref&gt;<br /> <br /> In another 2005 paper, Ioannidis analyzed &quot;49 of the most highly regarded research findings in medicine over the previous 13 years&quot;. The paper compared the 45 studies that claimed to have uncovered effective interventions to subsequent studies with larger sample sizes: 7 (16%) of the studies were contradicted, 7 (16%) had effects that were smaller in the second study than in the first, 20 (44%) were replicated, and 11 (24%) remained largely unchallenged.&lt;ref name=&quot;Ioannidis2005b&quot;&gt;{{cite pmid| 16014596}}&lt;/ref&gt;<br /> <br /> He has made many other influential empirical evaluations addressing the validation and replication performance of different types of studies in diverse scientific fields, including genetics,&lt;ref&gt;{{Cite journal|title = Replication validity of genetic association studies|url = http://www.nature.com/ng/journal/v29/n3/abs/ng749.html|journal = Nature Genetics|date = 2001-11-01|issn = 1061-4036|pages = 306–309|volume = 29|issue = 3|doi = 10.1038/ng749|first = John P. A.|last = Ioannidis|first2 = Evangelia E.|last2 = Ntzani|first3 = Thomas A.|last3 = Trikalinos|first4 = Despina G.|last4 = Contopoulos-Ioannidis}}&lt;/ref&gt; clinical trials,&lt;ref&gt;{{Cite journal|title = REanalyses of randomized clinical trial data|url = http://dx.doi.org/10.1001/jama.2014.9646|journal = JAMA|date = 2014-09-10|issn = 0098-7484|pages = 1024–1032|volume = 312|issue = 10|doi = 10.1001/jama.2014.9646}}&lt;/ref&gt; and neuroscience.&lt;ref&gt;{{Cite journal|title = Power failure: why small sample size undermines the reliability of neuroscience|url = http://www.nature.com/nrn/journal/v14/n5/full/nrn3475.html|journal = Nature Reviews Neuroscience|date = 2013-05-01|issn = 1471-003X|pages = 365–376|volume = 14|issue = 5|doi = 10.1038/nrn3475|first = Katherine S.|last = Button|first2 = John P. A.|last2 = Ioannidis|first3 = Claire|last3 = Mokrysz|first4 = Brian A.|last4 = Nosek|first5 = Jonathan|last5 = Flint|first6 = Emma S. J.|last6 = Robinson|first7 = Marcus R.|last7 = Munafò}}&lt;/ref&gt; His work has also aimed to identify solutions on how to optimize research practices&lt;ref&gt;{{Cite journal|title = Reproducibility in science: improving the standard for basic and preclinical research|url = http://www.ncbi.nlm.nih.gov/pubmed/25552691|journal = Circulation Research|date = 2015-01-02|issn = 1524-4571|pmid = 25552691|pages = 116–126|volume = 116|issue = 1|doi = 10.1161/CIRCRESAHA.114.303819|first = C. Glenn|last = Begley|first2 = John P. A.|last2 = Ioannidis}}&lt;/ref&gt; and to increase the yield of validated and useful scientific findings.&lt;ref&gt;{{Cite journal|title = How to Make More Published Research True|url = http://dx.doi.org/10.1371/journal.pmed.1001747|journal = PLoS Med|date = 2014-10-21|pmc = 4204808|pmid = 25334033|pages = e1001747|volume = 11|issue = 10|doi = 10.1371/journal.pmed.1001747|first = John P. A.|last = Ioannidis}}&lt;/ref&gt;<br /> <br /> He also coined the term [[Proteus phenomenon]] for the occurrence of extreme contradictory results in the early studies performed on the same research question. He has also made a number of contributions in<br /> the field of meta-analysis (the science of combining data from multiple studies on the same research question) and has been President of the Society for Research Synthesis Methodology.<br /> <br /> ==See also==<br /> * [[Reproducibility]]<br /> * [[Reproducibility Project]]<br /> * [[Publication bias]]<br /> * [[Meta-analysis]]<br /> <br /> ==References==<br /> {{Reflist}}<br /> <br /> ==External links==<br /> * [http://prevention.stanford.edu/ Prevention Research Center] Stanford School of Medicine<br /> *[https://med.stanford.edu/profiles/john-ioannidis?tab=publications Publications of John Ioannidis] Stanford University Profile<br /> * [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)62227-8/fulltext Increasing value and reducing waste in research design, conduct, and analysis] The Lancet, Volume 383, Issue 9912, Pages 166 - 175, 11 January 2014 John P A Ioannidis, Sander Greenland, Mark A Hlatky, Muin J Khoury, Malcolm R Macleod, David Moher, Kenneth F Schulzand Robert Tibshirani<br /> * ''[http://www.szgene.org/ Szgene.org]'', meta-analytic database of schizophrenia gene studies of which Dr. Ioannidis helped create.<br /> <br /> {{Authority control}}<br /> <br /> {{Persondata<br /> | NAME = Ioannidis, John P. A.<br /> | ALTERNATIVE NAMES =<br /> | SHORT DESCRIPTION = Greek epidemiologist<br /> | DATE OF BIRTH = August 21, 1965<br /> | PLACE OF BIRTH =<br /> | DATE OF DEATH =<br /> | PLACE OF DEATH =<br /> }}<br /> {{DEFAULTSORT:Ioannidis, John P. A.}}<br /> [[Category:Greek physicians]]<br /> [[Category:Living people]]<br /> [[Category:1965 births]]<br /> [[Category:Epidemiologists]]<br /> [[Category:Stanford University School of Medicine faculty]]</div> AppliedStatistics https://de.wikipedia.org/w/index.php?title=John_Ioannidis&diff=163728360 John Ioannidis 2015-10-25T03:17:40Z <p>AppliedStatistics: Links fixed</p> <hr /> <div>{{Infobox scientist<br /> | name = John P. A. Ioannidis<br /> | image = &lt;!--(filename only, i.e. without &quot;File:&quot; prefix)--&gt;<br /> | image_size = <br /> | alt = <br /> | caption = <br /> | birth_date = {{birth date and age |1965|8|21|mf=y}}<br /> | birth_place = <br /> | death_date = <br /> | death_place = <br /> | death_cause = <br /> | nationality = [[Greek American]]<br /> | fields = [[Medicine]]<br /> | workplaces = [[Stanford School of Medicine]]<br /> | alma_mater = [[University of Athens Medical School]]&lt;br&gt;[[Athens College]]<br /> | doctoral_advisor = &lt;!--(or | doctoral_advisors = )--&gt;<br /> | academic_advisors = <br /> | doctoral_students = <br /> | notable_students = <br /> | known_for = <br /> | influences = <br /> | influenced = <br /> | awards = <br /> }}<br /> <br /> '''John P. A. Ioannidis''' (born August 21, 1965, in New York City) is a Professor of Medicine and of Health Research and Policy at [[Stanford University School of Medicine]] and a Professor of Statistics at Stanford University School of Humanities and Sciences. He is director of the Stanford Prevention Research Center, and co-director, along with [[Steven N Goodman]], of the [[Meta-Research Innovation Center at Stanford]] (METRICS).&lt;ref&gt;{{cite web|url=https://med.stanford.edu/profiles/john-ioannidis|title = John P. A. Ioannidis|publisher = [[Stanford School of Medicine]] CAP Profiles|accessdate = May 24, 2014}}&lt;/ref&gt;&lt;ref&gt;{{cite web|url=http://prevention.stanford.edu/|title = Prevention Research Center |publisher= [[Stanford School of Medicine]]|accessdate = May 24, 2014}}&lt;/ref&gt; He was chairman at the Department of Hygiene and Epidemiology, [[University of Ioannina]] School of Medicine as well as [[adjunct professor]] at [[Tufts University School of Medicine]].&lt;ref&gt;{{Cite web<br /> | title = John P. A. Ioannidis<br /> | url = http://users.uoi.gr/hyepilab/people.php<br /> | publisher = Department of Hygiene and Epidemiology, [[University of Ioannina School of Medicine]]<br /> | accessdate = 2008-12-31<br /> }}&lt;/ref&gt;&lt;ref&gt;{{cite web<br /> |last=Ioannidis<br /> |first=John P.A.<br /> |title=Curriculum Vitae<br /> |url=http://www.dhe.med.uoi.gr/data/cv/CV102010D.pdf<br /> |accessdate=4 November 2010<br /> }}&lt;/ref&gt; He is best known for his research and published papers on scientific studies, particularly the 2005 paper &quot;Why Most Published Research Findings Are False&quot;.&lt;ref&gt;{{Cite journal|title = Why Most Published Research Findings Are False|url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182327/|journal = PLoS Medicine|date = 2005-08-01|issn = 1549-1277|pmc = 1182327|pmid = 16060722|volume = 2|issue = 8|doi = 10.1371/journal.pmed.0020124|first = John P. A.|last = Ioannidis}}&lt;/ref&gt; Ioannidis is one of the most-cited scientists across the scientific literature, especially in the fields of clinical medicine and social sciences, according to Thomson Reuters' Highly Cited Researchers 2015.&lt;ref&gt;{{Cite web|title = Home {{!}} Highly Cited Researchers|url = http://highlycited.com/|website = Highly Cited Researchers|accessdate = 2015-09-17}}&lt;/ref&gt;<br /> <br /> ==Biography==<br /> [[File:Ioannidis (2005) Why Most Published Research Findings Are False..pdf|thumb|Ioannidis (2005) Why Most Published Research Findings Are False.&lt;ref name=Ioannidis2005/&gt;]]<br /> Born in New York City in 1965, Ioannidis was raised in [[Athens]], [[Greece]].&lt;ref&gt;[http://www.hsph.harvard.edu/john-ioannidis/ John Ioannidis] Harvard School of Public Health&lt;/ref&gt; He was [[Valedictorian]] of his class at [[Athens College]], graduating in 1984. He also graduated first in his class at the [[University of Athens Medical School]], then attended [[Harvard University]] for his [[medical residency]] in [[internal medicine]]. He did a [[fellowship (medicine)|fellowship]] at [[Tufts University]] for [[infectious disease]]&lt;ref name=wrong&gt;{{cite book |author=[[David H. Freedman]] |coauthors= |title=Wrong: Why Experts Keep Failing Us|year=2010 |publisher=[[Little, Brown and Company]] |page= |quote=Born in 1965 in the United States to parents who were both physicians, he was raised in Athens, where he showed unusual aptitude in mathematics and snagged Greece's top student math prize. ... |url=http://books.google.com/books?id=XS4TQgAACAAJ&amp;dq |isbn=0-316-02378-7 }}&lt;/ref&gt; and came to Stanford in 2010.<br /> <br /> ===Press Coverage===<br /> The Atlantic wrote a lengthy piece on Ioannidis in 2010.&lt;ref&gt;{{cite magazine |author=[[David H. Freedman]]|title=&quot;Lies, damned lies, and medical science.&quot; |publisher=[[The Atlantic]]|page= 306.4 (2010): 76-84.|url=http://www.theatlantic.com/magazine/archive/2010/11/lies-damned-lies-and-medical-science/308269/}}&lt;/ref&gt;&lt;br&gt;<br /> <br /> The Economist wrote a shorter piece on Ioannidis in 2014 about the foundation, with [[Steven Goodman]], of the [[Meta-Research Innovation Centre]] at [[Stanford University]].&lt;ref&gt;{{cite magazine |title=&quot;Combating bad science: Metaphysicians&quot;|publisher=[[The Economist]]|url=http://www.economist.com/news/science-and-technology/21598944-sloppy-researchers-beware-new-institute-has-you-its-sights-metaphysicians/}}&lt;/ref&gt;<br /> <br /> ==Research findings==<br /> <br /> Ioannidis's 2005 paper &quot;Why Most Published Research Findings Are False&quot;&lt;ref name=Ioannidis2005&gt;{{Cite journal | last1 = Ioannidis | first1 = J. P. A. | authorlink1 = John P. A. Ioannidis| title = Why Most Published Research Findings Are False | journal = PLoS Medicine | volume = 2 | issue = 8 | pages = e124 | year = 2005 | pmid = 16060722 | pmc = 1182327 | doi = 10.1371/journal.pmed.0020124}}&lt;/ref&gt; has been the most downloaded technical paper from the journal ''[[PLoS Medicine]]''.&lt;ref&gt;{{Cite news<br /> | author = [[Robert Lee Hotz]]<br /> | title = Most Science Studies Appear to Be Tainted By Sloppy Analysis<br /> | url = http://online.wsj.com/public/article_print/SB118972683557627104.html<br /> | work = Science Journal WSJ.com<br /> | publisher = Dow Jones &amp; Company<br /> | date = 2007-09-14<br /> }}&lt;/ref&gt;<br /> <br /> In another 2005 paper, Ioannidis analyzed &quot;49 of the most highly regarded research findings in medicine over the previous 13 years&quot;. The paper compared the 45 studies that claimed to have uncovered effective interventions to subsequent studies with larger sample sizes: 7 (16%) of the studies were contradicted, 7 (16%) had effects that were smaller in the second study than in the first, 20 (44%) were replicated, and 11 (24%) remained largely unchallenged.&lt;ref name=&quot;Ioannidis2005b&quot;&gt;{{cite pmid| 16014596}}&lt;/ref&gt;<br /> <br /> He has made many other influential empirical evaluations addressing the validation and replication performance of different types of studies in diverse scientific fields, including genetics,&lt;ref&gt;{{Cite journal|title = Replication validity of genetic association studies|url = http://www.nature.com/ng/journal/v29/n3/abs/ng749.html|journal = Nature Genetics|date = 2001-11-01|issn = 1061-4036|pages = 306–309|volume = 29|issue = 3|doi = 10.1038/ng749|first = John P. A.|last = Ioannidis|first2 = Evangelia E.|last2 = Ntzani|first3 = Thomas A.|last3 = Trikalinos|first4 = Despina G.|last4 = Contopoulos-Ioannidis}}&lt;/ref&gt; clinical trials,&lt;ref&gt;{{Cite journal|title = REanalyses of randomized clinical trial data|url = http://dx.doi.org/10.1001/jama.2014.9646|journal = JAMA|date = 2014-09-10|issn = 0098-7484|pages = 1024–1032|volume = 312|issue = 10|doi = 10.1001/jama.2014.9646}}&lt;/ref&gt; and neuroscience.&lt;ref&gt;{{Cite journal|title = Power failure: why small sample size undermines the reliability of neuroscience|url = http://www.nature.com/nrn/journal/v14/n5/full/nrn3475.html|journal = Nature Reviews Neuroscience|date = 2013-05-01|issn = 1471-003X|pages = 365–376|volume = 14|issue = 5|doi = 10.1038/nrn3475|first = Katherine S.|last = Button|first2 = John P. A.|last2 = Ioannidis|first3 = Claire|last3 = Mokrysz|first4 = Brian A.|last4 = Nosek|first5 = Jonathan|last5 = Flint|first6 = Emma S. J.|last6 = Robinson|first7 = Marcus R.|last7 = Munafò}}&lt;/ref&gt; His work has also aimed to identify solutions on how to optimize research practices&lt;ref&gt;{{Cite journal|title = Reproducibility in science: improving the standard for basic and preclinical research|url = http://www.ncbi.nlm.nih.gov/pubmed/25552691|journal = Circulation Research|date = 2015-01-02|issn = 1524-4571|pmid = 25552691|pages = 116–126|volume = 116|issue = 1|doi = 10.1161/CIRCRESAHA.114.303819|first = C. Glenn|last = Begley|first2 = John P. A.|last2 = Ioannidis}}&lt;/ref&gt; and to increase the yield of validated and useful scientific findings.&lt;ref&gt;{{Cite journal|title = How to Make More Published Research True|url = http://dx.doi.org/10.1371/journal.pmed.1001747|journal = PLoS Med|date = 2014-10-21|pmc = 4204808|pmid = 25334033|pages = e1001747|volume = 11|issue = 10|doi = 10.1371/journal.pmed.1001747|first = John P. A.|last = Ioannidis}}&lt;/ref&gt;<br /> <br /> He also coined the term [[Proteus phenomenon]] for the occurrence of extreme contradictory results in the early studies performed on the same research question. He has also made a number of contributions in<br /> the field of meta-analysis (the science of combining data from multiple studies on the same research question) and has been President of the Society for Research Synthesis Methodology.<br /> <br /> ==See also==<br /> * [[Reproducibility]]<br /> * [[Reproducibility Project]]<br /> * [[Publication bias]]<br /> * [[Meta-analysis]]<br /> <br /> ==References==<br /> {{Reflist}}<br /> <br /> ==External links==<br /> * [http://prevention.stanford.edu/ Prevention Research Center] Stanford School of Medicine<br /> *[https://med.stanford.edu/profiles/john-ioannidis?tab=publications Publications of John Ioannidis] Stanford University Profile<br /> * [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)62227-8/fulltext Increasing value and reducing waste in research design, conduct, and analysis] The Lancet, Volume 383, Issue 9912, Pages 166 - 175, 11 January 2014 John P A Ioannidis, Sander Greenland, Mark A Hlatky, Muin J Khoury, Malcolm R Macleod, David Moher, Kenneth F Schulzand Robert Tibshirani<br /> * ''[http://www.szgene.org/ Szgene.org]'', meta-analytic database of schizophrenia gene studies of which Dr. Ioannidis helped create.<br /> <br /> {{Authority control}}<br /> <br /> {{Persondata<br /> | NAME = Ioannidis, John P. A.<br /> | ALTERNATIVE NAMES =<br /> | SHORT DESCRIPTION = Greek epidemiologist<br /> | DATE OF BIRTH = August 21, 1965<br /> | PLACE OF BIRTH =<br /> | DATE OF DEATH =<br /> | PLACE OF DEATH =<br /> }}<br /> {{DEFAULTSORT:Ioannidis, John P. A.}}<br /> [[Category:Greek physicians]]<br /> [[Category:Living people]]<br /> [[Category:1965 births]]<br /> [[Category:Epidemiologists]]<br /> [[Category:Stanford University School of Medicine faculty]]</div> AppliedStatistics https://de.wikipedia.org/w/index.php?title=John_Ioannidis&diff=163728359 John Ioannidis 2015-10-25T02:46:25Z <p>AppliedStatistics: /* Press Coverage */</p> <hr /> <div>{{Infobox scientist<br /> | name = John P. A. Ioannidis<br /> | image = &lt;!--(filename only, i.e. without &quot;File:&quot; prefix)--&gt;<br /> | image_size = <br /> | alt = <br /> | caption = <br /> | birth_date = {{birth date and age |1965|8|21|mf=y}}<br /> | birth_place = <br /> | death_date = <br /> | death_place = <br /> | death_cause = <br /> | nationality = [[Greek American]]<br /> | fields = [[Medicine]]<br /> | workplaces = [[Stanford School of Medicine]]<br /> | alma_mater = [[University of Athens Medical School]]&lt;br&gt;[[Athens College]]<br /> | doctoral_advisor = &lt;!--(or | doctoral_advisors = )--&gt;<br /> | academic_advisors = <br /> | doctoral_students = <br /> | notable_students = <br /> | known_for = <br /> | influences = <br /> | influenced = <br /> | awards = <br /> }}<br /> <br /> '''John P. A. Ioannidis''' (born August 21, 1965, in New York City) is a Professor of Medicine and of Health Research and Policy at [[Stanford University School of Medicine]] and a Professor of Statistics at Stanford University School of Humanities and Sciences. He is director of the Stanford Prevention Research Center, and co-director, along with Steven Goodman, of the [[Meta-Research Innovation Center at Stanford]] (METRICS).&lt;ref&gt;{{cite web|url=https://med.stanford.edu/profiles/john-ioannidis|title = John P. A. Ioannidis|publisher = [[Stanford School of Medicine]] CAP Profiles|accessdate = May 24, 2014}}&lt;/ref&gt;&lt;ref&gt;{{cite web|url=http://prevention.stanford.edu/|title = Prevention Research Center |publisher= [[Stanford School of Medicine]]|accessdate = May 24, 2014}}&lt;/ref&gt; He was chairman at the Department of Hygiene and Epidemiology, [[University of Ioannina]] School of Medicine as well as [[adjunct professor]] at [[Tufts University School of Medicine]].&lt;ref&gt;{{Cite web<br /> | title = John P. A. Ioannidis<br /> | url = http://users.uoi.gr/hyepilab/people.php<br /> | publisher = Department of Hygiene and Epidemiology, [[University of Ioannina School of Medicine]]<br /> | accessdate = 2008-12-31<br /> }}&lt;/ref&gt;&lt;ref&gt;{{cite web<br /> |last=Ioannidis<br /> |first=John P.A.<br /> |title=Curriculum Vitae<br /> |url=http://www.dhe.med.uoi.gr/data/cv/CV102010D.pdf<br /> |accessdate=4 November 2010<br /> }}&lt;/ref&gt; He is best known for his research and published papers on scientific studies, particularly the 2005 paper &quot;Why Most Published Research Findings Are False&quot;.&lt;ref&gt;{{Cite journal|title = Why Most Published Research Findings Are False|url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182327/|journal = PLoS Medicine|date = 2005-08-01|issn = 1549-1277|pmc = 1182327|pmid = 16060722|volume = 2|issue = 8|doi = 10.1371/journal.pmed.0020124|first = John P. A.|last = Ioannidis}}&lt;/ref&gt; Ioannidis is one of the most-cited scientists across the scientific literature, especially in the fields of clinical medicine and social sciences, according to Thomson Reuters' Highly Cited Researchers 2015.&lt;ref&gt;{{Cite web|title = Home {{!}} Highly Cited Researchers|url = http://highlycited.com/|website = Highly Cited Researchers|accessdate = 2015-09-17}}&lt;/ref&gt;<br /> <br /> ==Biography==<br /> [[File:Ioannidis (2005) Why Most Published Research Findings Are False..pdf|thumb|Ioannidis (2005) Why Most Published Research Findings Are False.&lt;ref name=Ioannidis2005/&gt;]]<br /> Born in New York City in 1965, Ioannidis was raised in [[Athens]], [[Greece]].&lt;ref&gt;[http://www.hsph.harvard.edu/john-ioannidis/ John Ioannidis] Harvard School of Public Health&lt;/ref&gt; He was [[Valedictorian]] of his class at [[Athens College]], graduating in 1984. He also graduated first in his class at the [[University of Athens Medical School]], then attended [[Harvard University]] for his [[medical residency]] in [[internal medicine]]. He did a [[fellowship (medicine)|fellowship]] at [[Tufts University]] for [[infectious disease]]&lt;ref name=wrong&gt;{{cite book |author=[[David H. Freedman]] |coauthors= |title=Wrong: Why Experts Keep Failing Us|year=2010 |publisher=[[Little, Brown and Company]] |page= |quote=Born in 1965 in the United States to parents who were both physicians, he was raised in Athens, where he showed unusual aptitude in mathematics and snagged Greece's top student math prize. ... |url=http://books.google.com/books?id=XS4TQgAACAAJ&amp;dq |isbn=0-316-02378-7 }}&lt;/ref&gt; and came to Stanford in 2010.<br /> <br /> ===Press Coverage===<br /> The Atlantic wrote a lengthy piece on Ioannidis in 2010.&lt;ref&gt;{{cite magazine |author=[[David H. Freedman]]|title=&quot;Lies, damned lies, and medical science.&quot; |publisher=[[The Atlantic]]|page= 306.4 (2010): 76-84.|url=http://www.theatlantic.com/magazine/archive/2010/11/lies-damned-lies-and-medical-science/308269/}}&lt;/ref&gt;&lt;br&gt;<br /> <br /> The Economist wrote a shorter piece on Ioannidis in 2014 about the foundation, with [[Steven Goodman]], of the [[Meta-Research Innovation Centre]] at [[Stanford University]].&lt;ref&gt;{{cite magazine |title=&quot;Combating bad science: Metaphysicians&quot;|publisher=[[The Economist]]|url=http://www.economist.com/news/science-and-technology/21598944-sloppy-researchers-beware-new-institute-has-you-its-sights-metaphysicians/}}&lt;/ref&gt;<br /> <br /> ==Research findings==<br /> <br /> Ioannidis's 2005 paper &quot;Why Most Published Research Findings Are False&quot;&lt;ref name=Ioannidis2005&gt;{{Cite journal | last1 = Ioannidis | first1 = J. P. A. | authorlink1 = John P. A. Ioannidis| title = Why Most Published Research Findings Are False | journal = PLoS Medicine | volume = 2 | issue = 8 | pages = e124 | year = 2005 | pmid = 16060722 | pmc = 1182327 | doi = 10.1371/journal.pmed.0020124}}&lt;/ref&gt; has been the most downloaded technical paper from the journal ''[[PLoS Medicine]]''.&lt;ref&gt;{{Cite news<br /> | author = [[Robert Lee Hotz]]<br /> | title = Most Science Studies Appear to Be Tainted By Sloppy Analysis<br /> | url = http://online.wsj.com/public/article_print/SB118972683557627104.html<br /> | work = Science Journal WSJ.com<br /> | publisher = Dow Jones &amp; Company<br /> | date = 2007-09-14<br /> }}&lt;/ref&gt;<br /> <br /> In another 2005 paper, Ioannidis analyzed &quot;49 of the most highly regarded research findings in medicine over the previous 13 years&quot;. The paper compared the 45 studies that claimed to have uncovered effective interventions to subsequent studies with larger sample sizes: 7 (16%) of the studies were contradicted, 7 (16%) had effects that were smaller in the second study than in the first, 20 (44%) were replicated, and 11 (24%) remained largely unchallenged.&lt;ref name=&quot;Ioannidis2005b&quot;&gt;{{cite pmid| 16014596}}&lt;/ref&gt;<br /> <br /> He has made many other influential empirical evaluations addressing the validation and replication performance of different types of studies in diverse scientific fields, including genetics,&lt;ref&gt;{{Cite journal|title = Replication validity of genetic association studies|url = http://www.nature.com/ng/journal/v29/n3/abs/ng749.html|journal = Nature Genetics|date = 2001-11-01|issn = 1061-4036|pages = 306–309|volume = 29|issue = 3|doi = 10.1038/ng749|first = John P. A.|last = Ioannidis|first2 = Evangelia E.|last2 = Ntzani|first3 = Thomas A.|last3 = Trikalinos|first4 = Despina G.|last4 = Contopoulos-Ioannidis}}&lt;/ref&gt; clinical trials,&lt;ref&gt;{{Cite journal|title = REanalyses of randomized clinical trial data|url = http://dx.doi.org/10.1001/jama.2014.9646|journal = JAMA|date = 2014-09-10|issn = 0098-7484|pages = 1024–1032|volume = 312|issue = 10|doi = 10.1001/jama.2014.9646}}&lt;/ref&gt; and neuroscience.&lt;ref&gt;{{Cite journal|title = Power failure: why small sample size undermines the reliability of neuroscience|url = http://www.nature.com/nrn/journal/v14/n5/full/nrn3475.html|journal = Nature Reviews Neuroscience|date = 2013-05-01|issn = 1471-003X|pages = 365–376|volume = 14|issue = 5|doi = 10.1038/nrn3475|first = Katherine S.|last = Button|first2 = John P. A.|last2 = Ioannidis|first3 = Claire|last3 = Mokrysz|first4 = Brian A.|last4 = Nosek|first5 = Jonathan|last5 = Flint|first6 = Emma S. J.|last6 = Robinson|first7 = Marcus R.|last7 = Munafò}}&lt;/ref&gt; His work has also aimed to identify solutions on how to optimize research practices&lt;ref&gt;{{Cite journal|title = Reproducibility in science: improving the standard for basic and preclinical research|url = http://www.ncbi.nlm.nih.gov/pubmed/25552691|journal = Circulation Research|date = 2015-01-02|issn = 1524-4571|pmid = 25552691|pages = 116–126|volume = 116|issue = 1|doi = 10.1161/CIRCRESAHA.114.303819|first = C. Glenn|last = Begley|first2 = John P. A.|last2 = Ioannidis}}&lt;/ref&gt; and to increase the yield of validated and useful scientific findings.&lt;ref&gt;{{Cite journal|title = How to Make More Published Research True|url = http://dx.doi.org/10.1371/journal.pmed.1001747|journal = PLoS Med|date = 2014-10-21|pmc = 4204808|pmid = 25334033|pages = e1001747|volume = 11|issue = 10|doi = 10.1371/journal.pmed.1001747|first = John P. A.|last = Ioannidis}}&lt;/ref&gt;<br /> <br /> He also coined the term [[Proteus phenomenon]] for the occurrence of extreme contradictory results in the early studies performed on the same research question. He has also made a number of contributions in<br /> the field of meta-analysis (the science of combining data from multiple studies on the same research question) and has been President of the Society for Research Synthesis Methodology.<br /> <br /> ==See also==<br /> * [[Reproducibility]]<br /> * [[Reproducibility Project]]<br /> * [[Publication bias]]<br /> * [[Meta-analysis]]<br /> <br /> ==References==<br /> {{Reflist}}<br /> <br /> ==External links==<br /> * [http://prevention.stanford.edu/ Prevention Research Center] Stanford School of Medicine<br /> *[https://med.stanford.edu/profiles/john-ioannidis?tab=publications Publications of John Ioannidis] Stanford University Profile<br /> * [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)62227-8/fulltext Increasing value and reducing waste in research design, conduct, and analysis] The Lancet, Volume 383, Issue 9912, Pages 166 - 175, 11 January 2014 John P A Ioannidis, Sander Greenland, Mark A Hlatky, Muin J Khoury, Malcolm R Macleod, David Moher, Kenneth F Schulzand Robert Tibshirani<br /> * ''[http://www.szgene.org/ Szgene.org]'', meta-analytic database of schizophrenia gene studies of which Dr. Ioannidis helped create.<br /> <br /> {{Authority control}}<br /> <br /> {{Persondata<br /> | NAME = Ioannidis, John P. A.<br /> | ALTERNATIVE NAMES =<br /> | SHORT DESCRIPTION = Greek epidemiologist<br /> | DATE OF BIRTH = August 21, 1965<br /> | PLACE OF BIRTH =<br /> | DATE OF DEATH =<br /> | PLACE OF DEATH =<br /> }}<br /> {{DEFAULTSORT:Ioannidis, John P. A.}}<br /> [[Category:Greek physicians]]<br /> [[Category:Living people]]<br /> [[Category:1965 births]]<br /> [[Category:Epidemiologists]]<br /> [[Category:Stanford University School of Medicine faculty]]</div> AppliedStatistics https://de.wikipedia.org/w/index.php?title=John_Ioannidis&diff=163728358 John Ioannidis 2015-10-25T02:39:34Z <p>AppliedStatistics: /* Press Coverage */ fixup</p> <hr /> <div>{{Infobox scientist<br /> | name = John P. A. Ioannidis<br /> | image = &lt;!--(filename only, i.e. without &quot;File:&quot; prefix)--&gt;<br /> | image_size = <br /> | alt = <br /> | caption = <br /> | birth_date = {{birth date and age |1965|8|21|mf=y}}<br /> | birth_place = <br /> | death_date = <br /> | death_place = <br /> | death_cause = <br /> | nationality = [[Greek American]]<br /> | fields = [[Medicine]]<br /> | workplaces = [[Stanford School of Medicine]]<br /> | alma_mater = [[University of Athens Medical School]]&lt;br&gt;[[Athens College]]<br /> | doctoral_advisor = &lt;!--(or | doctoral_advisors = )--&gt;<br /> | academic_advisors = <br /> | doctoral_students = <br /> | notable_students = <br /> | known_for = <br /> | influences = <br /> | influenced = <br /> | awards = <br /> }}<br /> <br /> '''John P. A. Ioannidis''' (born August 21, 1965, in New York City) is a Professor of Medicine and of Health Research and Policy at [[Stanford University School of Medicine]] and a Professor of Statistics at Stanford University School of Humanities and Sciences. He is director of the Stanford Prevention Research Center, and co-director, along with Steven Goodman, of the [[Meta-Research Innovation Center at Stanford]] (METRICS).&lt;ref&gt;{{cite web|url=https://med.stanford.edu/profiles/john-ioannidis|title = John P. A. Ioannidis|publisher = [[Stanford School of Medicine]] CAP Profiles|accessdate = May 24, 2014}}&lt;/ref&gt;&lt;ref&gt;{{cite web|url=http://prevention.stanford.edu/|title = Prevention Research Center |publisher= [[Stanford School of Medicine]]|accessdate = May 24, 2014}}&lt;/ref&gt; He was chairman at the Department of Hygiene and Epidemiology, [[University of Ioannina]] School of Medicine as well as [[adjunct professor]] at [[Tufts University School of Medicine]].&lt;ref&gt;{{Cite web<br /> | title = John P. A. Ioannidis<br /> | url = http://users.uoi.gr/hyepilab/people.php<br /> | publisher = Department of Hygiene and Epidemiology, [[University of Ioannina School of Medicine]]<br /> | accessdate = 2008-12-31<br /> }}&lt;/ref&gt;&lt;ref&gt;{{cite web<br /> |last=Ioannidis<br /> |first=John P.A.<br /> |title=Curriculum Vitae<br /> |url=http://www.dhe.med.uoi.gr/data/cv/CV102010D.pdf<br /> |accessdate=4 November 2010<br /> }}&lt;/ref&gt; He is best known for his research and published papers on scientific studies, particularly the 2005 paper &quot;Why Most Published Research Findings Are False&quot;.&lt;ref&gt;{{Cite journal|title = Why Most Published Research Findings Are False|url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182327/|journal = PLoS Medicine|date = 2005-08-01|issn = 1549-1277|pmc = 1182327|pmid = 16060722|volume = 2|issue = 8|doi = 10.1371/journal.pmed.0020124|first = John P. A.|last = Ioannidis}}&lt;/ref&gt; Ioannidis is one of the most-cited scientists across the scientific literature, especially in the fields of clinical medicine and social sciences, according to Thomson Reuters' Highly Cited Researchers 2015.&lt;ref&gt;{{Cite web|title = Home {{!}} Highly Cited Researchers|url = http://highlycited.com/|website = Highly Cited Researchers|accessdate = 2015-09-17}}&lt;/ref&gt;<br /> <br /> ==Biography==<br /> [[File:Ioannidis (2005) Why Most Published Research Findings Are False..pdf|thumb|Ioannidis (2005) Why Most Published Research Findings Are False.&lt;ref name=Ioannidis2005/&gt;]]<br /> Born in New York City in 1965, Ioannidis was raised in [[Athens]], [[Greece]].&lt;ref&gt;[http://www.hsph.harvard.edu/john-ioannidis/ John Ioannidis] Harvard School of Public Health&lt;/ref&gt; He was [[Valedictorian]] of his class at [[Athens College]], graduating in 1984. He also graduated first in his class at the [[University of Athens Medical School]], then attended [[Harvard University]] for his [[medical residency]] in [[internal medicine]]. He did a [[fellowship (medicine)|fellowship]] at [[Tufts University]] for [[infectious disease]]&lt;ref name=wrong&gt;{{cite book |author=[[David H. Freedman]] |coauthors= |title=Wrong: Why Experts Keep Failing Us|year=2010 |publisher=[[Little, Brown and Company]] |page= |quote=Born in 1965 in the United States to parents who were both physicians, he was raised in Athens, where he showed unusual aptitude in mathematics and snagged Greece's top student math prize. ... |url=http://books.google.com/books?id=XS4TQgAACAAJ&amp;dq |isbn=0-316-02378-7 }}&lt;/ref&gt; and came to Stanford in 2010.<br /> <br /> ===Press Coverage===<br /> The Atlantic wrote a lengthy piece on Ioannidis in 2010.&lt;ref&gt;{{cite magazine |author=[[David H. Freedman]]|title=&quot;Lies, damned lies, and medical science.&quot; |publisher=[[The Atlantic]]|page= 306.4 (2010): 76-84.|url=http://www.theatlantic.com/magazine/archive/2010/11/lies-damned-lies-and-medical-science/308269/}}&lt;/ref&gt;&lt;br&gt;<br /> <br /> The Economist wrote a shorter piece on Ioannidis in 2014 about the foundation, with Steven Goodman, of the Meta-Research Innovation Centre at Stanford.&lt;ref&gt;{{cite magazine |title=&quot;Combating bad science: Metaphysicians&quot;|publisher=[[The Economist]]|url=http://www.economist.com/news/science-and-technology/21598944-sloppy-researchers-beware-new-institute-has-you-its-sights-metaphysicians/}}&lt;/ref&gt;<br /> <br /> ==Research findings==<br /> <br /> Ioannidis's 2005 paper &quot;Why Most Published Research Findings Are False&quot;&lt;ref name=Ioannidis2005&gt;{{Cite journal | last1 = Ioannidis | first1 = J. P. A. | authorlink1 = John P. A. Ioannidis| title = Why Most Published Research Findings Are False | journal = PLoS Medicine | volume = 2 | issue = 8 | pages = e124 | year = 2005 | pmid = 16060722 | pmc = 1182327 | doi = 10.1371/journal.pmed.0020124}}&lt;/ref&gt; has been the most downloaded technical paper from the journal ''[[PLoS Medicine]]''.&lt;ref&gt;{{Cite news<br /> | author = [[Robert Lee Hotz]]<br /> | title = Most Science Studies Appear to Be Tainted By Sloppy Analysis<br /> | url = http://online.wsj.com/public/article_print/SB118972683557627104.html<br /> | work = Science Journal WSJ.com<br /> | publisher = Dow Jones &amp; Company<br /> | date = 2007-09-14<br /> }}&lt;/ref&gt;<br /> <br /> In another 2005 paper, Ioannidis analyzed &quot;49 of the most highly regarded research findings in medicine over the previous 13 years&quot;. The paper compared the 45 studies that claimed to have uncovered effective interventions to subsequent studies with larger sample sizes: 7 (16%) of the studies were contradicted, 7 (16%) had effects that were smaller in the second study than in the first, 20 (44%) were replicated, and 11 (24%) remained largely unchallenged.&lt;ref name=&quot;Ioannidis2005b&quot;&gt;{{cite pmid| 16014596}}&lt;/ref&gt;<br /> <br /> He has made many other influential empirical evaluations addressing the validation and replication performance of different types of studies in diverse scientific fields, including genetics,&lt;ref&gt;{{Cite journal|title = Replication validity of genetic association studies|url = http://www.nature.com/ng/journal/v29/n3/abs/ng749.html|journal = Nature Genetics|date = 2001-11-01|issn = 1061-4036|pages = 306–309|volume = 29|issue = 3|doi = 10.1038/ng749|first = John P. A.|last = Ioannidis|first2 = Evangelia E.|last2 = Ntzani|first3 = Thomas A.|last3 = Trikalinos|first4 = Despina G.|last4 = Contopoulos-Ioannidis}}&lt;/ref&gt; clinical trials,&lt;ref&gt;{{Cite journal|title = REanalyses of randomized clinical trial data|url = http://dx.doi.org/10.1001/jama.2014.9646|journal = JAMA|date = 2014-09-10|issn = 0098-7484|pages = 1024–1032|volume = 312|issue = 10|doi = 10.1001/jama.2014.9646}}&lt;/ref&gt; and neuroscience.&lt;ref&gt;{{Cite journal|title = Power failure: why small sample size undermines the reliability of neuroscience|url = http://www.nature.com/nrn/journal/v14/n5/full/nrn3475.html|journal = Nature Reviews Neuroscience|date = 2013-05-01|issn = 1471-003X|pages = 365–376|volume = 14|issue = 5|doi = 10.1038/nrn3475|first = Katherine S.|last = Button|first2 = John P. A.|last2 = Ioannidis|first3 = Claire|last3 = Mokrysz|first4 = Brian A.|last4 = Nosek|first5 = Jonathan|last5 = Flint|first6 = Emma S. J.|last6 = Robinson|first7 = Marcus R.|last7 = Munafò}}&lt;/ref&gt; His work has also aimed to identify solutions on how to optimize research practices&lt;ref&gt;{{Cite journal|title = Reproducibility in science: improving the standard for basic and preclinical research|url = http://www.ncbi.nlm.nih.gov/pubmed/25552691|journal = Circulation Research|date = 2015-01-02|issn = 1524-4571|pmid = 25552691|pages = 116–126|volume = 116|issue = 1|doi = 10.1161/CIRCRESAHA.114.303819|first = C. Glenn|last = Begley|first2 = John P. A.|last2 = Ioannidis}}&lt;/ref&gt; and to increase the yield of validated and useful scientific findings.&lt;ref&gt;{{Cite journal|title = How to Make More Published Research True|url = http://dx.doi.org/10.1371/journal.pmed.1001747|journal = PLoS Med|date = 2014-10-21|pmc = 4204808|pmid = 25334033|pages = e1001747|volume = 11|issue = 10|doi = 10.1371/journal.pmed.1001747|first = John P. A.|last = Ioannidis}}&lt;/ref&gt;<br /> <br /> He also coined the term [[Proteus phenomenon]] for the occurrence of extreme contradictory results in the early studies performed on the same research question. He has also made a number of contributions in<br /> the field of meta-analysis (the science of combining data from multiple studies on the same research question) and has been President of the Society for Research Synthesis Methodology.<br /> <br /> ==See also==<br /> * [[Reproducibility]]<br /> * [[Reproducibility Project]]<br /> * [[Publication bias]]<br /> * [[Meta-analysis]]<br /> <br /> ==References==<br /> {{Reflist}}<br /> <br /> ==External links==<br /> * [http://prevention.stanford.edu/ Prevention Research Center] Stanford School of Medicine<br /> *[https://med.stanford.edu/profiles/john-ioannidis?tab=publications Publications of John Ioannidis] Stanford University Profile<br /> * [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)62227-8/fulltext Increasing value and reducing waste in research design, conduct, and analysis] The Lancet, Volume 383, Issue 9912, Pages 166 - 175, 11 January 2014 John P A Ioannidis, Sander Greenland, Mark A Hlatky, Muin J Khoury, Malcolm R Macleod, David Moher, Kenneth F Schulzand Robert Tibshirani<br /> * ''[http://www.szgene.org/ Szgene.org]'', meta-analytic database of schizophrenia gene studies of which Dr. Ioannidis helped create.<br /> <br /> {{Authority control}}<br /> <br /> {{Persondata<br /> | NAME = Ioannidis, John P. A.<br /> | ALTERNATIVE NAMES =<br /> | SHORT DESCRIPTION = Greek epidemiologist<br /> | DATE OF BIRTH = August 21, 1965<br /> | PLACE OF BIRTH =<br /> | DATE OF DEATH =<br /> | PLACE OF DEATH =<br /> }}<br /> {{DEFAULTSORT:Ioannidis, John P. A.}}<br /> [[Category:Greek physicians]]<br /> [[Category:Living people]]<br /> [[Category:1965 births]]<br /> [[Category:Epidemiologists]]<br /> [[Category:Stanford University School of Medicine faculty]]</div> AppliedStatistics https://de.wikipedia.org/w/index.php?title=John_Ioannidis&diff=163728357 John Ioannidis 2015-10-25T02:38:13Z <p>AppliedStatistics: /* Press Coverage */</p> <hr /> <div>{{Infobox scientist<br /> | name = John P. A. Ioannidis<br /> | image = &lt;!--(filename only, i.e. without &quot;File:&quot; prefix)--&gt;<br /> | image_size = <br /> | alt = <br /> | caption = <br /> | birth_date = {{birth date and age |1965|8|21|mf=y}}<br /> | birth_place = <br /> | death_date = <br /> | death_place = <br /> | death_cause = <br /> | nationality = [[Greek American]]<br /> | fields = [[Medicine]]<br /> | workplaces = [[Stanford School of Medicine]]<br /> | alma_mater = [[University of Athens Medical School]]&lt;br&gt;[[Athens College]]<br /> | doctoral_advisor = &lt;!--(or | doctoral_advisors = )--&gt;<br /> | academic_advisors = <br /> | doctoral_students = <br /> | notable_students = <br /> | known_for = <br /> | influences = <br /> | influenced = <br /> | awards = <br /> }}<br /> <br /> '''John P. A. Ioannidis''' (born August 21, 1965, in New York City) is a Professor of Medicine and of Health Research and Policy at [[Stanford University School of Medicine]] and a Professor of Statistics at Stanford University School of Humanities and Sciences. He is director of the Stanford Prevention Research Center, and co-director, along with Steven Goodman, of the [[Meta-Research Innovation Center at Stanford]] (METRICS).&lt;ref&gt;{{cite web|url=https://med.stanford.edu/profiles/john-ioannidis|title = John P. A. Ioannidis|publisher = [[Stanford School of Medicine]] CAP Profiles|accessdate = May 24, 2014}}&lt;/ref&gt;&lt;ref&gt;{{cite web|url=http://prevention.stanford.edu/|title = Prevention Research Center |publisher= [[Stanford School of Medicine]]|accessdate = May 24, 2014}}&lt;/ref&gt; He was chairman at the Department of Hygiene and Epidemiology, [[University of Ioannina]] School of Medicine as well as [[adjunct professor]] at [[Tufts University School of Medicine]].&lt;ref&gt;{{Cite web<br /> | title = John P. A. Ioannidis<br /> | url = http://users.uoi.gr/hyepilab/people.php<br /> | publisher = Department of Hygiene and Epidemiology, [[University of Ioannina School of Medicine]]<br /> | accessdate = 2008-12-31<br /> }}&lt;/ref&gt;&lt;ref&gt;{{cite web<br /> |last=Ioannidis<br /> |first=John P.A.<br /> |title=Curriculum Vitae<br /> |url=http://www.dhe.med.uoi.gr/data/cv/CV102010D.pdf<br /> |accessdate=4 November 2010<br /> }}&lt;/ref&gt; He is best known for his research and published papers on scientific studies, particularly the 2005 paper &quot;Why Most Published Research Findings Are False&quot;.&lt;ref&gt;{{Cite journal|title = Why Most Published Research Findings Are False|url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182327/|journal = PLoS Medicine|date = 2005-08-01|issn = 1549-1277|pmc = 1182327|pmid = 16060722|volume = 2|issue = 8|doi = 10.1371/journal.pmed.0020124|first = John P. A.|last = Ioannidis}}&lt;/ref&gt; Ioannidis is one of the most-cited scientists across the scientific literature, especially in the fields of clinical medicine and social sciences, according to Thomson Reuters' Highly Cited Researchers 2015.&lt;ref&gt;{{Cite web|title = Home {{!}} Highly Cited Researchers|url = http://highlycited.com/|website = Highly Cited Researchers|accessdate = 2015-09-17}}&lt;/ref&gt;<br /> <br /> ==Biography==<br /> [[File:Ioannidis (2005) Why Most Published Research Findings Are False..pdf|thumb|Ioannidis (2005) Why Most Published Research Findings Are False.&lt;ref name=Ioannidis2005/&gt;]]<br /> Born in New York City in 1965, Ioannidis was raised in [[Athens]], [[Greece]].&lt;ref&gt;[http://www.hsph.harvard.edu/john-ioannidis/ John Ioannidis] Harvard School of Public Health&lt;/ref&gt; He was [[Valedictorian]] of his class at [[Athens College]], graduating in 1984. He also graduated first in his class at the [[University of Athens Medical School]], then attended [[Harvard University]] for his [[medical residency]] in [[internal medicine]]. He did a [[fellowship (medicine)|fellowship]] at [[Tufts University]] for [[infectious disease]]&lt;ref name=wrong&gt;{{cite book |author=[[David H. Freedman]] |coauthors= |title=Wrong: Why Experts Keep Failing Us|year=2010 |publisher=[[Little, Brown and Company]] |page= |quote=Born in 1965 in the United States to parents who were both physicians, he was raised in Athens, where he showed unusual aptitude in mathematics and snagged Greece's top student math prize. ... |url=http://books.google.com/books?id=XS4TQgAACAAJ&amp;dq |isbn=0-316-02378-7 }}&lt;/ref&gt; and came to Stanford in 2010.<br /> <br /> ===Press Coverage===<br /> The Atlantic wrote a lengthy piece on Ioannidis in 2010.&lt;ref&gt;{{cite magazine |author=[[David H. Freedman]]|title=&quot;Lies, damned lies, and medical science.&quot; |publisher=[[The Atlantic]]|page= 306.4 (2010): 76-84.|url=http://www.theatlantic.com/magazine/archive/2010/11/lies-damned-lies-and-medical-science/308269/}}&lt;/ref&gt;&lt;br&gt;<br /> The Economist wrote a shorter piece on Ioannidis in 2014 about the foundation, with Steven Goodman, of the Meta-Research Innovation Centre at Stanford.&lt;ref&gt;{{cite magazine |author=[[David H. Freedman]]|title=&quot;Lies, damned lies, and medical science.&quot; |publisher=[[The Economist]]|url=http://www.economist.com/news/science-and-technology/21598944-sloppy-researchers-beware-new-institute-has-you-its-sights-metaphysicians/}}&lt;/ref&gt;<br /> <br /> ==Research findings==<br /> <br /> Ioannidis's 2005 paper &quot;Why Most Published Research Findings Are False&quot;&lt;ref name=Ioannidis2005&gt;{{Cite journal | last1 = Ioannidis | first1 = J. P. A. | authorlink1 = John P. A. Ioannidis| title = Why Most Published Research Findings Are False | journal = PLoS Medicine | volume = 2 | issue = 8 | pages = e124 | year = 2005 | pmid = 16060722 | pmc = 1182327 | doi = 10.1371/journal.pmed.0020124}}&lt;/ref&gt; has been the most downloaded technical paper from the journal ''[[PLoS Medicine]]''.&lt;ref&gt;{{Cite news<br /> | author = [[Robert Lee Hotz]]<br /> | title = Most Science Studies Appear to Be Tainted By Sloppy Analysis<br /> | url = http://online.wsj.com/public/article_print/SB118972683557627104.html<br /> | work = Science Journal WSJ.com<br /> | publisher = Dow Jones &amp; Company<br /> | date = 2007-09-14<br /> }}&lt;/ref&gt;<br /> <br /> In another 2005 paper, Ioannidis analyzed &quot;49 of the most highly regarded research findings in medicine over the previous 13 years&quot;. The paper compared the 45 studies that claimed to have uncovered effective interventions to subsequent studies with larger sample sizes: 7 (16%) of the studies were contradicted, 7 (16%) had effects that were smaller in the second study than in the first, 20 (44%) were replicated, and 11 (24%) remained largely unchallenged.&lt;ref name=&quot;Ioannidis2005b&quot;&gt;{{cite pmid| 16014596}}&lt;/ref&gt;<br /> <br /> He has made many other influential empirical evaluations addressing the validation and replication performance of different types of studies in diverse scientific fields, including genetics,&lt;ref&gt;{{Cite journal|title = Replication validity of genetic association studies|url = http://www.nature.com/ng/journal/v29/n3/abs/ng749.html|journal = Nature Genetics|date = 2001-11-01|issn = 1061-4036|pages = 306–309|volume = 29|issue = 3|doi = 10.1038/ng749|first = John P. A.|last = Ioannidis|first2 = Evangelia E.|last2 = Ntzani|first3 = Thomas A.|last3 = Trikalinos|first4 = Despina G.|last4 = Contopoulos-Ioannidis}}&lt;/ref&gt; clinical trials,&lt;ref&gt;{{Cite journal|title = REanalyses of randomized clinical trial data|url = http://dx.doi.org/10.1001/jama.2014.9646|journal = JAMA|date = 2014-09-10|issn = 0098-7484|pages = 1024–1032|volume = 312|issue = 10|doi = 10.1001/jama.2014.9646}}&lt;/ref&gt; and neuroscience.&lt;ref&gt;{{Cite journal|title = Power failure: why small sample size undermines the reliability of neuroscience|url = http://www.nature.com/nrn/journal/v14/n5/full/nrn3475.html|journal = Nature Reviews Neuroscience|date = 2013-05-01|issn = 1471-003X|pages = 365–376|volume = 14|issue = 5|doi = 10.1038/nrn3475|first = Katherine S.|last = Button|first2 = John P. A.|last2 = Ioannidis|first3 = Claire|last3 = Mokrysz|first4 = Brian A.|last4 = Nosek|first5 = Jonathan|last5 = Flint|first6 = Emma S. J.|last6 = Robinson|first7 = Marcus R.|last7 = Munafò}}&lt;/ref&gt; His work has also aimed to identify solutions on how to optimize research practices&lt;ref&gt;{{Cite journal|title = Reproducibility in science: improving the standard for basic and preclinical research|url = http://www.ncbi.nlm.nih.gov/pubmed/25552691|journal = Circulation Research|date = 2015-01-02|issn = 1524-4571|pmid = 25552691|pages = 116–126|volume = 116|issue = 1|doi = 10.1161/CIRCRESAHA.114.303819|first = C. Glenn|last = Begley|first2 = John P. A.|last2 = Ioannidis}}&lt;/ref&gt; and to increase the yield of validated and useful scientific findings.&lt;ref&gt;{{Cite journal|title = How to Make More Published Research True|url = http://dx.doi.org/10.1371/journal.pmed.1001747|journal = PLoS Med|date = 2014-10-21|pmc = 4204808|pmid = 25334033|pages = e1001747|volume = 11|issue = 10|doi = 10.1371/journal.pmed.1001747|first = John P. A.|last = Ioannidis}}&lt;/ref&gt;<br /> <br /> He also coined the term [[Proteus phenomenon]] for the occurrence of extreme contradictory results in the early studies performed on the same research question. He has also made a number of contributions in<br /> the field of meta-analysis (the science of combining data from multiple studies on the same research question) and has been President of the Society for Research Synthesis Methodology.<br /> <br /> ==See also==<br /> * [[Reproducibility]]<br /> * [[Reproducibility Project]]<br /> * [[Publication bias]]<br /> * [[Meta-analysis]]<br /> <br /> ==References==<br /> {{Reflist}}<br /> <br /> ==External links==<br /> * [http://prevention.stanford.edu/ Prevention Research Center] Stanford School of Medicine<br /> *[https://med.stanford.edu/profiles/john-ioannidis?tab=publications Publications of John Ioannidis] Stanford University Profile<br /> * [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)62227-8/fulltext Increasing value and reducing waste in research design, conduct, and analysis] The Lancet, Volume 383, Issue 9912, Pages 166 - 175, 11 January 2014 John P A Ioannidis, Sander Greenland, Mark A Hlatky, Muin J Khoury, Malcolm R Macleod, David Moher, Kenneth F Schulzand Robert Tibshirani<br /> * ''[http://www.szgene.org/ Szgene.org]'', meta-analytic database of schizophrenia gene studies of which Dr. Ioannidis helped create.<br /> <br /> {{Authority control}}<br /> <br /> {{Persondata<br /> | NAME = Ioannidis, John P. A.<br /> | ALTERNATIVE NAMES =<br /> | SHORT DESCRIPTION = Greek epidemiologist<br /> | DATE OF BIRTH = August 21, 1965<br /> | PLACE OF BIRTH =<br /> | DATE OF DEATH =<br /> | PLACE OF DEATH =<br /> }}<br /> {{DEFAULTSORT:Ioannidis, John P. A.}}<br /> [[Category:Greek physicians]]<br /> [[Category:Living people]]<br /> [[Category:1965 births]]<br /> [[Category:Epidemiologists]]<br /> [[Category:Stanford University School of Medicine faculty]]</div> AppliedStatistics https://de.wikipedia.org/w/index.php?title=John_Ioannidis&diff=163728356 John Ioannidis 2015-10-25T02:37:03Z <p>AppliedStatistics: /* Press Coverage */ Further coverage</p> <hr /> <div>{{Infobox scientist<br /> | name = John P. A. Ioannidis<br /> | image = &lt;!--(filename only, i.e. without &quot;File:&quot; prefix)--&gt;<br /> | image_size = <br /> | alt = <br /> | caption = <br /> | birth_date = {{birth date and age |1965|8|21|mf=y}}<br /> | birth_place = <br /> | death_date = <br /> | death_place = <br /> | death_cause = <br /> | nationality = [[Greek American]]<br /> | fields = [[Medicine]]<br /> | workplaces = [[Stanford School of Medicine]]<br /> | alma_mater = [[University of Athens Medical School]]&lt;br&gt;[[Athens College]]<br /> | doctoral_advisor = &lt;!--(or | doctoral_advisors = )--&gt;<br /> | academic_advisors = <br /> | doctoral_students = <br /> | notable_students = <br /> | known_for = <br /> | influences = <br /> | influenced = <br /> | awards = <br /> }}<br /> <br /> '''John P. A. Ioannidis''' (born August 21, 1965, in New York City) is a Professor of Medicine and of Health Research and Policy at [[Stanford University School of Medicine]] and a Professor of Statistics at Stanford University School of Humanities and Sciences. He is director of the Stanford Prevention Research Center, and co-director, along with Steven Goodman, of the [[Meta-Research Innovation Center at Stanford]] (METRICS).&lt;ref&gt;{{cite web|url=https://med.stanford.edu/profiles/john-ioannidis|title = John P. A. Ioannidis|publisher = [[Stanford School of Medicine]] CAP Profiles|accessdate = May 24, 2014}}&lt;/ref&gt;&lt;ref&gt;{{cite web|url=http://prevention.stanford.edu/|title = Prevention Research Center |publisher= [[Stanford School of Medicine]]|accessdate = May 24, 2014}}&lt;/ref&gt; He was chairman at the Department of Hygiene and Epidemiology, [[University of Ioannina]] School of Medicine as well as [[adjunct professor]] at [[Tufts University School of Medicine]].&lt;ref&gt;{{Cite web<br /> | title = John P. A. Ioannidis<br /> | url = http://users.uoi.gr/hyepilab/people.php<br /> | publisher = Department of Hygiene and Epidemiology, [[University of Ioannina School of Medicine]]<br /> | accessdate = 2008-12-31<br /> }}&lt;/ref&gt;&lt;ref&gt;{{cite web<br /> |last=Ioannidis<br /> |first=John P.A.<br /> |title=Curriculum Vitae<br /> |url=http://www.dhe.med.uoi.gr/data/cv/CV102010D.pdf<br /> |accessdate=4 November 2010<br /> }}&lt;/ref&gt; He is best known for his research and published papers on scientific studies, particularly the 2005 paper &quot;Why Most Published Research Findings Are False&quot;.&lt;ref&gt;{{Cite journal|title = Why Most Published Research Findings Are False|url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182327/|journal = PLoS Medicine|date = 2005-08-01|issn = 1549-1277|pmc = 1182327|pmid = 16060722|volume = 2|issue = 8|doi = 10.1371/journal.pmed.0020124|first = John P. A.|last = Ioannidis}}&lt;/ref&gt; Ioannidis is one of the most-cited scientists across the scientific literature, especially in the fields of clinical medicine and social sciences, according to Thomson Reuters' Highly Cited Researchers 2015.&lt;ref&gt;{{Cite web|title = Home {{!}} Highly Cited Researchers|url = http://highlycited.com/|website = Highly Cited Researchers|accessdate = 2015-09-17}}&lt;/ref&gt;<br /> <br /> ==Biography==<br /> [[File:Ioannidis (2005) Why Most Published Research Findings Are False..pdf|thumb|Ioannidis (2005) Why Most Published Research Findings Are False.&lt;ref name=Ioannidis2005/&gt;]]<br /> Born in New York City in 1965, Ioannidis was raised in [[Athens]], [[Greece]].&lt;ref&gt;[http://www.hsph.harvard.edu/john-ioannidis/ John Ioannidis] Harvard School of Public Health&lt;/ref&gt; He was [[Valedictorian]] of his class at [[Athens College]], graduating in 1984. He also graduated first in his class at the [[University of Athens Medical School]], then attended [[Harvard University]] for his [[medical residency]] in [[internal medicine]]. He did a [[fellowship (medicine)|fellowship]] at [[Tufts University]] for [[infectious disease]]&lt;ref name=wrong&gt;{{cite book |author=[[David H. Freedman]] |coauthors= |title=Wrong: Why Experts Keep Failing Us|year=2010 |publisher=[[Little, Brown and Company]] |page= |quote=Born in 1965 in the United States to parents who were both physicians, he was raised in Athens, where he showed unusual aptitude in mathematics and snagged Greece's top student math prize. ... |url=http://books.google.com/books?id=XS4TQgAACAAJ&amp;dq |isbn=0-316-02378-7 }}&lt;/ref&gt; and came to Stanford in 2010.<br /> <br /> ===Press Coverage===<br /> The Atlantic wrote a lengthy piece on Ioannidis in 2010.&lt;ref&gt;{{cite magazine |author=[[David H. Freedman]]|title=&quot;Lies, damned lies, and medical science.&quot; |publisher=[[The Atlantic]]|page= 306.4 (2010): 76-84.|url=http://www.theatlantic.com/magazine/archive/2010/11/lies-damned-lies-and-medical-science/308269/}}&lt;/ref&gt;<br /> The Economist wrote a shorter piece on Ioannidis in 2014 about the foundation, with Steven Goodman, of the Meta-Research Innovation Centre at Stanford.&lt;ref&gt;{{cite magazine |author=[[David H. Freedman]]|title=&quot;Lies, damned lies, and medical science.&quot; |publisher=[[The Atlantic]]|page= 306.4 (2010): 76-84.|url=http://www.theatlantic.com/magazine/archive/2010/11/lies-damned-lies-and-medical-science/308269/}}&lt;/ref&gt;<br /> <br /> ==Research findings==<br /> <br /> Ioannidis's 2005 paper &quot;Why Most Published Research Findings Are False&quot;&lt;ref name=Ioannidis2005&gt;{{Cite journal | last1 = Ioannidis | first1 = J. P. A. | authorlink1 = John P. A. Ioannidis| title = Why Most Published Research Findings Are False | journal = PLoS Medicine | volume = 2 | issue = 8 | pages = e124 | year = 2005 | pmid = 16060722 | pmc = 1182327 | doi = 10.1371/journal.pmed.0020124}}&lt;/ref&gt; has been the most downloaded technical paper from the journal ''[[PLoS Medicine]]''.&lt;ref&gt;{{Cite news<br /> | author = [[Robert Lee Hotz]]<br /> | title = Most Science Studies Appear to Be Tainted By Sloppy Analysis<br /> | url = http://online.wsj.com/public/article_print/SB118972683557627104.html<br /> | work = Science Journal WSJ.com<br /> | publisher = Dow Jones &amp; Company<br /> | date = 2007-09-14<br /> }}&lt;/ref&gt;<br /> <br /> In another 2005 paper, Ioannidis analyzed &quot;49 of the most highly regarded research findings in medicine over the previous 13 years&quot;. The paper compared the 45 studies that claimed to have uncovered effective interventions to subsequent studies with larger sample sizes: 7 (16%) of the studies were contradicted, 7 (16%) had effects that were smaller in the second study than in the first, 20 (44%) were replicated, and 11 (24%) remained largely unchallenged.&lt;ref name=&quot;Ioannidis2005b&quot;&gt;{{cite pmid| 16014596}}&lt;/ref&gt;<br /> <br /> He has made many other influential empirical evaluations addressing the validation and replication performance of different types of studies in diverse scientific fields, including genetics,&lt;ref&gt;{{Cite journal|title = Replication validity of genetic association studies|url = http://www.nature.com/ng/journal/v29/n3/abs/ng749.html|journal = Nature Genetics|date = 2001-11-01|issn = 1061-4036|pages = 306–309|volume = 29|issue = 3|doi = 10.1038/ng749|first = John P. A.|last = Ioannidis|first2 = Evangelia E.|last2 = Ntzani|first3 = Thomas A.|last3 = Trikalinos|first4 = Despina G.|last4 = Contopoulos-Ioannidis}}&lt;/ref&gt; clinical trials,&lt;ref&gt;{{Cite journal|title = REanalyses of randomized clinical trial data|url = http://dx.doi.org/10.1001/jama.2014.9646|journal = JAMA|date = 2014-09-10|issn = 0098-7484|pages = 1024–1032|volume = 312|issue = 10|doi = 10.1001/jama.2014.9646}}&lt;/ref&gt; and neuroscience.&lt;ref&gt;{{Cite journal|title = Power failure: why small sample size undermines the reliability of neuroscience|url = http://www.nature.com/nrn/journal/v14/n5/full/nrn3475.html|journal = Nature Reviews Neuroscience|date = 2013-05-01|issn = 1471-003X|pages = 365–376|volume = 14|issue = 5|doi = 10.1038/nrn3475|first = Katherine S.|last = Button|first2 = John P. A.|last2 = Ioannidis|first3 = Claire|last3 = Mokrysz|first4 = Brian A.|last4 = Nosek|first5 = Jonathan|last5 = Flint|first6 = Emma S. J.|last6 = Robinson|first7 = Marcus R.|last7 = Munafò}}&lt;/ref&gt; His work has also aimed to identify solutions on how to optimize research practices&lt;ref&gt;{{Cite journal|title = Reproducibility in science: improving the standard for basic and preclinical research|url = http://www.ncbi.nlm.nih.gov/pubmed/25552691|journal = Circulation Research|date = 2015-01-02|issn = 1524-4571|pmid = 25552691|pages = 116–126|volume = 116|issue = 1|doi = 10.1161/CIRCRESAHA.114.303819|first = C. Glenn|last = Begley|first2 = John P. A.|last2 = Ioannidis}}&lt;/ref&gt; and to increase the yield of validated and useful scientific findings.&lt;ref&gt;{{Cite journal|title = How to Make More Published Research True|url = http://dx.doi.org/10.1371/journal.pmed.1001747|journal = PLoS Med|date = 2014-10-21|pmc = 4204808|pmid = 25334033|pages = e1001747|volume = 11|issue = 10|doi = 10.1371/journal.pmed.1001747|first = John P. A.|last = Ioannidis}}&lt;/ref&gt;<br /> <br /> He also coined the term [[Proteus phenomenon]] for the occurrence of extreme contradictory results in the early studies performed on the same research question. He has also made a number of contributions in<br /> the field of meta-analysis (the science of combining data from multiple studies on the same research question) and has been President of the Society for Research Synthesis Methodology.<br /> <br /> ==See also==<br /> * [[Reproducibility]]<br /> * [[Reproducibility Project]]<br /> * [[Publication bias]]<br /> * [[Meta-analysis]]<br /> <br /> ==References==<br /> {{Reflist}}<br /> <br /> ==External links==<br /> * [http://prevention.stanford.edu/ Prevention Research Center] Stanford School of Medicine<br /> *[https://med.stanford.edu/profiles/john-ioannidis?tab=publications Publications of John Ioannidis] Stanford University Profile<br /> * [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)62227-8/fulltext Increasing value and reducing waste in research design, conduct, and analysis] The Lancet, Volume 383, Issue 9912, Pages 166 - 175, 11 January 2014 John P A Ioannidis, Sander Greenland, Mark A Hlatky, Muin J Khoury, Malcolm R Macleod, David Moher, Kenneth F Schulzand Robert Tibshirani<br /> * ''[http://www.szgene.org/ Szgene.org]'', meta-analytic database of schizophrenia gene studies of which Dr. Ioannidis helped create.<br /> <br /> {{Authority control}}<br /> <br /> {{Persondata<br /> | NAME = Ioannidis, John P. A.<br /> | ALTERNATIVE NAMES =<br /> | SHORT DESCRIPTION = Greek epidemiologist<br /> | DATE OF BIRTH = August 21, 1965<br /> | PLACE OF BIRTH =<br /> | DATE OF DEATH =<br /> | PLACE OF DEATH =<br /> }}<br /> {{DEFAULTSORT:Ioannidis, John P. A.}}<br /> [[Category:Greek physicians]]<br /> [[Category:Living people]]<br /> [[Category:1965 births]]<br /> [[Category:Epidemiologists]]<br /> [[Category:Stanford University School of Medicine faculty]]</div> AppliedStatistics https://de.wikipedia.org/w/index.php?title=John_Ioannidis&diff=163728354 John Ioannidis 2015-10-09T20:38:35Z <p>AppliedStatistics: </p> <hr /> <div>{{Infobox scientist<br /> | name = John P. A. Ioannidis<br /> | image = &lt;!--(filename only, i.e. without &quot;File:&quot; prefix)--&gt;<br /> | image_size = <br /> | alt = <br /> | caption = <br /> | birth_date = {{birth date and age |1965|8|21|mf=y}}<br /> | birth_place = <br /> | death_date = <br /> | death_place = <br /> | death_cause = <br /> | nationality = [[Greek American]]<br /> | fields = [[Medicine]]<br /> | workplaces = [[Stanford School of Medicine]]<br /> | alma_mater = [[University of Athens Medical School]]&lt;br&gt;[[Athens College]]<br /> | doctoral_advisor = &lt;!--(or | doctoral_advisors = )--&gt;<br /> | academic_advisors = <br /> | doctoral_students = <br /> | notable_students = <br /> | known_for = <br /> | influences = <br /> | influenced = <br /> | awards = <br /> }}<br /> <br /> '''John P. A. Ioannidis''' (born August 21, 1965, in New York City) is a Professor of Medicine and of Health Research and Policy at [[Stanford University School of Medicine]] and a Professor of Statistics at Stanford University School of Humanities and Sciences. He is director of the Stanford Prevention Research Center, and co-director, along with Steven Goodman, of the [[Meta-Research Innovation Center at Stanford]] (METRICS).&lt;ref&gt;{{cite web|url=https://med.stanford.edu/profiles/john-ioannidis|title = John P. A. Ioannidis|publisher = [[Stanford School of Medicine]] CAP Profiles|accessdate = May 24, 2014}}&lt;/ref&gt;&lt;ref&gt;{{cite web|url=http://prevention.stanford.edu/|title = Prevention Research Center |publisher= [[Stanford School of Medicine]]|accessdate = May 24, 2014}}&lt;/ref&gt; He was chairman at the Department of Hygiene and Epidemiology, [[University of Ioannina]] School of Medicine as well as [[adjunct professor]] at [[Tufts University School of Medicine]].&lt;ref&gt;{{Cite web<br /> | title = John P. A. Ioannidis<br /> | url = http://users.uoi.gr/hyepilab/people.php<br /> | publisher = Department of Hygiene and Epidemiology, [[University of Ioannina School of Medicine]]<br /> | accessdate = 2008-12-31<br /> }}&lt;/ref&gt;&lt;ref&gt;{{cite web<br /> |last=Ioannidis<br /> |first=John P.A.<br /> |title=Curriculum Vitae<br /> |url=http://www.dhe.med.uoi.gr/data/cv/CV102010D.pdf<br /> |accessdate=4 November 2010<br /> }}&lt;/ref&gt; He is best known for his research and published papers on scientific studies, particularly the 2005 paper &quot;Why Most Published Research Findings Are False&quot;.&lt;ref&gt;{{Cite journal|title = Why Most Published Research Findings Are False|url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182327/|journal = PLoS Medicine|date = 2005-08-01|issn = 1549-1277|pmc = 1182327|pmid = 16060722|volume = 2|issue = 8|doi = 10.1371/journal.pmed.0020124|first = John P. A.|last = Ioannidis}}&lt;/ref&gt; Ioannidis is one of the most-cited scientists across the scientific literature, especially in the fields of clinical medicine and social sciences, according to Thomson Reuters' Highly Cited Researchers 2015.&lt;ref&gt;{{Cite web|title = Home {{!}} Highly Cited Researchers|url = http://highlycited.com/|website = Highly Cited Researchers|accessdate = 2015-09-17}}&lt;/ref&gt;<br /> <br /> ==Biography==<br /> [[File:Ioannidis (2005) Why Most Published Research Findings Are False..pdf|thumb|Ioannidis (2005) Why Most Published Research Findings Are False.&lt;ref name=Ioannidis2005/&gt;]]<br /> Born in New York City in 1965, Ioannidis was raised in [[Athens]], [[Greece]].&lt;ref&gt;[http://www.hsph.harvard.edu/john-ioannidis/ John Ioannidis] Harvard School of Public Health&lt;/ref&gt; He was [[Valedictorian]] of his class at [[Athens College]], graduating in 1984. He also graduated first in his class at the [[University of Athens Medical School]], then attended [[Harvard University]] for his [[medical residency]] in [[internal medicine]]. He did a [[fellowship (medicine)|fellowship]] at [[Tufts University]] for [[infectious disease]]&lt;ref name=wrong&gt;{{cite book |author=[[David H. Freedman]] |coauthors= |title=Wrong: Why Experts Keep Failing Us|year=2010 |publisher=[[Little, Brown and Company]] |page= |quote=Born in 1965 in the United States to parents who were both physicians, he was raised in Athens, where he showed unusual aptitude in mathematics and snagged Greece's top student math prize. ... |url=http://books.google.com/books?id=XS4TQgAACAAJ&amp;dq |isbn=0-316-02378-7 }}&lt;/ref&gt; and came to Stanford in 2010.<br /> <br /> ===Press Coverage===<br /> The Atlantic wrote a lengthy piece on Ioannidis in 2010&lt;ref&gt;{{cite magazine |author=[[David H. Freedman]]|title=&quot;Lies, damned lies, and medical science.&quot; |publisher=[[The Atlantic]]|page= 306.4 (2010): 76-84.|url=http://www.theatlantic.com/magazine/archive/2010/11/lies-damned-lies-and-medical-science/308269/}}&lt;/ref&gt;.<br /> <br /> <br /> ==Research findings==<br /> <br /> Ioannidis's 2005 paper &quot;Why Most Published Research Findings Are False&quot;&lt;ref name=Ioannidis2005&gt;{{Cite journal | last1 = Ioannidis | first1 = J. P. A. | authorlink1 = John P. A. Ioannidis| title = Why Most Published Research Findings Are False | journal = PLoS Medicine | volume = 2 | issue = 8 | pages = e124 | year = 2005 | pmid = 16060722 | pmc = 1182327 | doi = 10.1371/journal.pmed.0020124}}&lt;/ref&gt; has been the most downloaded technical paper from the journal ''[[PLoS Medicine]]''.&lt;ref&gt;{{Cite news<br /> | author = [[Robert Lee Hotz]]<br /> | title = Most Science Studies Appear to Be Tainted By Sloppy Analysis<br /> | url = http://online.wsj.com/public/article_print/SB118972683557627104.html<br /> | work = Science Journal WSJ.com<br /> | publisher = Dow Jones &amp; Company<br /> | date = 2007-09-14<br /> }}&lt;/ref&gt;<br /> <br /> In another 2005 paper, Ioannidis analyzed &quot;49 of the most highly regarded research findings in medicine over the previous 13 years&quot;. The paper compared the 45 studies that claimed to have uncovered effective interventions to subsequent studies with larger sample sizes: 7 (16%) of the studies were contradicted, 7 (16%) had effects that were smaller in the second study than in the first, 20 (44%) were replicated, and 11 (24%) remained largely unchallenged.&lt;ref name=&quot;Ioannidis2005b&quot;&gt;{{cite pmid| 16014596}}&lt;/ref&gt;<br /> <br /> He has made many other influential empirical evaluations addressing the validation and replication performance of different types of studies in diverse scientific fields, including genetics,&lt;ref&gt;{{Cite journal|title = Replication validity of genetic association studies|url = http://www.nature.com/ng/journal/v29/n3/abs/ng749.html|journal = Nature Genetics|date = 2001-11-01|issn = 1061-4036|pages = 306–309|volume = 29|issue = 3|doi = 10.1038/ng749|first = John P. A.|last = Ioannidis|first2 = Evangelia E.|last2 = Ntzani|first3 = Thomas A.|last3 = Trikalinos|first4 = Despina G.|last4 = Contopoulos-Ioannidis}}&lt;/ref&gt; clinical trials,&lt;ref&gt;{{Cite journal|title = REanalyses of randomized clinical trial data|url = http://dx.doi.org/10.1001/jama.2014.9646|journal = JAMA|date = 2014-09-10|issn = 0098-7484|pages = 1024–1032|volume = 312|issue = 10|doi = 10.1001/jama.2014.9646}}&lt;/ref&gt; and neuroscience.&lt;ref&gt;{{Cite journal|title = Power failure: why small sample size undermines the reliability of neuroscience|url = http://www.nature.com/nrn/journal/v14/n5/full/nrn3475.html|journal = Nature Reviews Neuroscience|date = 2013-05-01|issn = 1471-003X|pages = 365–376|volume = 14|issue = 5|doi = 10.1038/nrn3475|first = Katherine S.|last = Button|first2 = John P. A.|last2 = Ioannidis|first3 = Claire|last3 = Mokrysz|first4 = Brian A.|last4 = Nosek|first5 = Jonathan|last5 = Flint|first6 = Emma S. J.|last6 = Robinson|first7 = Marcus R.|last7 = Munafò}}&lt;/ref&gt; His work has also aimed to identify solutions on how to optimize research practices&lt;ref&gt;{{Cite journal|title = Reproducibility in science: improving the standard for basic and preclinical research|url = http://www.ncbi.nlm.nih.gov/pubmed/25552691|journal = Circulation Research|date = 2015-01-02|issn = 1524-4571|pmid = 25552691|pages = 116–126|volume = 116|issue = 1|doi = 10.1161/CIRCRESAHA.114.303819|first = C. Glenn|last = Begley|first2 = John P. A.|last2 = Ioannidis}}&lt;/ref&gt; and to increase the yield of validated and useful scientific findings.&lt;ref&gt;{{Cite journal|title = How to Make More Published Research True|url = http://dx.doi.org/10.1371/journal.pmed.1001747|journal = PLoS Med|date = 2014-10-21|pmc = 4204808|pmid = 25334033|pages = e1001747|volume = 11|issue = 10|doi = 10.1371/journal.pmed.1001747|first = John P. A.|last = Ioannidis}}&lt;/ref&gt;<br /> <br /> He also coined the term [[Proteus phenomenon]] for the occurrence of extreme contradictory results in the early studies performed on the same research question. He has also made a number of contributions in<br /> the field of meta-analysis (the science of combining data from multiple studies on the same research question) and has been President of the Society for Research Synthesis Methodology.<br /> <br /> ==See also==<br /> * [[Reproducibility]]<br /> * [[Reproducibility Project]]<br /> * [[Publication bias]]<br /> * [[Meta-analysis]]<br /> <br /> ==References==<br /> {{Reflist}}<br /> <br /> ==External links==<br /> * [http://prevention.stanford.edu/ Prevention Research Center] Stanford School of Medicine<br /> *[https://med.stanford.edu/profiles/john-ioannidis?tab=publications Publications of John Ioannidis] Stanford University Profile<br /> * [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)62227-8/fulltext Increasing value and reducing waste in research design, conduct, and analysis] The Lancet, Volume 383, Issue 9912, Pages 166 - 175, 11 January 2014 John P A Ioannidis, Sander Greenland, Mark A Hlatky, Muin J Khoury, Malcolm R Macleod, David Moher, Kenneth F Schulzand Robert Tibshirani<br /> * ''[http://www.szgene.org/ Szgene.org]'', meta-analytic database of schizophrenia gene studies of which Dr. Ioannidis helped create.<br /> <br /> {{Authority control}}<br /> <br /> {{Persondata<br /> | NAME = Ioannidis, John P. A.<br /> | ALTERNATIVE NAMES =<br /> | SHORT DESCRIPTION = Greek epidemiologist<br /> | DATE OF BIRTH = August 21, 1965<br /> | PLACE OF BIRTH =<br /> | DATE OF DEATH =<br /> | PLACE OF DEATH =<br /> }}<br /> {{DEFAULTSORT:Ioannidis, John P. A.}}<br /> [[Category:Greek physicians]]<br /> [[Category:Living people]]<br /> [[Category:1965 births]]<br /> [[Category:Epidemiologists]]<br /> [[Category:Stanford University School of Medicine faculty]]</div> AppliedStatistics